Phase 4 CTS Clinical Trials
24 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 24 trials
Recruiting
Phase 4
Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission
Healthy Adult FemalesThe Focus of the Study is to Investigate Reversible Effects of Combined Oral Contraceptive Use on Serotonergic Neurotransmission
Rigshospitalet, Denmark60 enrolled1 locationNCT07511439
Recruiting
Phase 4
Study to Evaluate a New Cartilage Regeneration Platform for Knee Cartilage Repair
Cartilage Defects of the Knee
ROKIT Healthcare104 enrolled13 locationsNCT07639424
Recruiting
Phase 4
Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures
Soft Tissue DefectsSoft Tissue WoundsTraumatic Soft Tissue Defect
Aroa Biosurgery Limited30 enrolled2 locationsNCT07385313
Recruiting
Phase 4
The Stimulation To Induce Mothers Study
Labor PainOxytocinPhysiologic Effects of Drugs+1 more
Yale University988 enrolled3 locationsNCT05079841
Recruiting
Phase 4
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients
ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4
Intracervical Vasopressin
Retained Products of Conception
Prisma Health-Upstate50 enrolled1 locationNCT07102615
Recruiting
Phase 4
HighCycle Study: Acetazolamide, High Altitude and Plasma Volume
WomenHigh Altitude EffectsHigh Altitude Hypoxia+2 more
Centre d'Expertise sur l'Altitude EXALT270 enrolled1 locationNCT07118462
Recruiting
Phase 4
The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma
ParagangliomaPheochromocytomaAdrenalectomy; Status+1 more
Seoul National University Hospital24 enrolled1 locationNCT05702944
Recruiting
Phase 4
Comparing a 'wait and watch' approach vs medical treatment with misoprostol for first trimester retained products of pregnancy and using ultrasound to predict success
Early pregnancy complicationFirst trimester retained products of conception
Nepean hospital80 enrolled1 locationACTRN12624001463561
Completed
Phase 4
Investigating Ketamine for treating the pain experienced by people bitten by a Red-Back Spider.
Pain from a red-back spider biteSystemic effects of envenoming by a red-back spider
University of Newcastle12 enrolled1 locationACTRN12616000889459
Completed
Phase 4
Efficacy of the tissue press method for reducing systemic side effects of eye drops compared to nasolacrimal occlusion
Adverse systemic effects of eye drops
Luzia Mueller20 enrolled1 locationACTRN12616000404426
Active
Phase 4
Sleep and speech: Objectively monitoring the residual effects of sleep-promoting compounds
Cognitive detriment due to residual effects to the central nervous system after using zolpidem or temazepam.
Monash University50 enrolled1 locationACTRN12616000033448
Not Yet Recruiting
Phase 4
The Restoring coronary arteries with drug eluting resorbable stents compared to metal stents in patients with diffuse narrowing. The RESTORE feasibility study
Subjects with diffuse left anterior descending artery disease that is not attractive for surgical revascularization
The University of Western Australia30 enrolled4 locationsACTRN12616000025437
Completed
Phase 4
A Prospective Randomised Trial of Two Tidal Volume Ventilator Strategies in Patients Undergoing Major Surgery
Effects of ventilation in patients undergoing major surgery
Departments of Intensive Care and Anaesthesia, Austin Hospital1,240 enrolled1 locationACTRN12614000790640
Completed
Phase 4
Understanding the behavioural effects of multivitamin supplements
The behavioural effects of multivitaminsThe influence of multivitamins on mood and cognition
Swinburne University86 enrolled1 locationACTRN12613001087741
Recruiting
Phase 4
Effects of Galvus (Vildagliptin) on Markers of Inflammation in Diabetic Foot Ulcer: A prospective, randomized, double-blind, placebo-controlled pilot study
Type 2 Diabetes
Diabetic Foot UlcerAnti-inflammatory effects of VildagliptinDiabetic foot ulcer healing properties of Vildagliptin
Assoc. Professor Usman H. Malabu; FRCPI, FRACP.50 enrolled1 locationACTRN12613000418774
Recruiting
Phase 4
The neuroendocrine and metabolic effects of oestrogens
Metabolic effects of oestrogensNeuroendocrine regulation of GH secretion by oestrogens
Garvan Institute of Medical Research20 enrolled1 locationACTRN12611001093976
Not Yet Recruiting
Phase 4
The acute effects of Yohimbine on fear conditioning and the neural processing of emotional images, and on delayed extinction learning and memory for the images.
Healthy subjects, investigating the mechanisms underpinning Post Traumatic Stress Disorder
University of New South Wales120 enrolled1 locationACTRN12611000820909
Not Yet Recruiting
Phase 4
The Effects of Parecoxib in Children
The Pharmacokinetic and Pharmacodynamics of Parecoxib.
The perioperative pain relief in children and the effects of parecoxib in children
Dr. Elsa Taylor75 enrolled1 locationACTRN12611000352909
Not Yet Recruiting
Phase 4
Effects of dipeptidyl peptidase IV (DPP-IV) inhibition (vildagliptin) on plasma concentrations of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) during intraduodenal fat infusion.
Physiological study to investigate the effects of intraduodenal fat in healthy volunteers.
Outcomes may have implications for type 2 diabetes and obesity.
Royal Adelaide Hospital16 enrolled1 locationACTRN12610001104044