Decompensated Heart Failure Clinical Trials

6 recruiting

Frequently Asked Questions

Common questions about Decompensated Heart Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 26 trials

Recruiting
Phase 1

Vericiguat in Decompensated Cardiac Failure: Clinical Insights on Addition to Guidelines Derived Medical Therapy-VERCIG Trial

Decompensated Heart Failure
Khawaja Danish Ali130 enrolled1 locationNCT07444398
Recruiting
Not Applicable

Reprieve System Pilot Study

Acute Decompensated Heart Failure
Reprieve Cardiovascular, Inc50 enrolled1 locationNCT06272734
Recruiting
Phase 2

Add-on Diuretics in Acute Decompensated Heart Failure

Acute Decompensated Heart Failure
Tanta University66 enrolled1 locationNCT07372040
Recruiting
Not Applicable

Use of Point-of-Care Ultrasound (POCUS) to Reduce Hospital Length of Stay in Patients With Heart Failure ( POCUSHF )

Heart FailureDecompensated Heart FailureHospital Length of Stay
Florida International University66 enrolled1 locationNCT06965712
Recruiting
Phase 3

Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure

Acute Decompensated Heart Failure (ADHF)
Christian Schulze536 enrolled1 locationNCT07038356
Recruiting
Phase 3

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Acute Decompensated Heart Failure
Reprieve Cardiovascular, Inc400 enrolled53 locationsNCT06898515
Recruiting
Not Applicable

Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure

Heart Failure, DiastolicAcute Decompensated Heart FailureHeart Failure, Systolic
University of Health Sciences Lahore320 enrolled1 locationNCT07199088
Recruiting
Not Applicable

Bioimpedance Integration for Optimized Fluid Management in Decompensated Heart Failure

Heart FailureDecompensated Heart Failure
Mid and South Essex NHS Foundation Trust255 enrolled1 locationNCT07173426
Recruiting
Not Applicable

BIO|CONCEPT.BIOMONITOR-HF Collect Clinical Data From Heart Failure Patients Using BIOMONITOR Devices With a Study Specific Research Software

Heart FailureAtrial FibrillationArrhythmia+1 more
Biotronik SE & Co. KG300 enrolled2 locationsNCT06989580
Recruiting
Phase 4

The Effect of Dapagliflozin on Patients With Cardiomyopathy

Acute Decompensated Heart Failure (ADHF)
May Mohamed Abdalla100 enrolled1 locationNCT07076615
Recruiting
Not Applicable

EACH-ADHF: Early Comprehensive Rehabilitation in Patients With ADHF

Acute Decompensated Heart Failure
Guangdong Provincial People's Hospital140 enrolled1 locationNCT06161987
Recruiting

Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure

Heart FailureAcute Decompensated Heart Failure
UConn Health500 enrolled1 locationNCT00762008
Recruiting
Not Applicable

Using an Intervention Adapted to the Health Literacy Level to Improve Adherence to Medical Recommendations

Acute Myocardial InfarctionAcute Decompensated Heart Failure
Hospices Civils de Lyon300 enrolled4 locationsNCT03951467
Recruiting
Not Applicable

Low Level Tragus Stimulation in Acute Decompensated Heart Failure

Acute Decompensated Heart Failure
University of Oklahoma100 enrolled1 locationNCT02898181
Recruiting
Not Applicable

Safety and Performance Evaluation of the Nephronyx System for the Treatment of Patients With ADHF

Acute Decompensated Heart Failure
Nephronyx LTD10 enrolled4 locationsNCT05759806
Recruiting

Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure

Acute Decompensated Heart Failure
NYU Langone Health50 enrolled1 locationNCT05240651
Recruiting

A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure

Heart FailureDecompensated Heart Failure
Royal Brompton & Harefield NHS Foundation Trust150 enrolled1 locationNCT06397833
Recruiting
Not Applicable

Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure

Heart FailureAcute Kidney InjuryAcute Decompensated Heart Failure+1 more
Oslo University Hospital180 enrolled1 locationNCT06714409
Recruiting
Phase 4

Combination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure Outcomes

Acute Decompensated Heart Failure
Universitas Diponegoro66 enrolled2 locationsNCT06475105
Recruiting

The Association Between Visual Echocardiographic Scoring System and Clinical Outcomes in Patient With Acute Decompensated Heart Failure

Acute Decompensated Heart Failure
Universitas Diponegoro150 enrolled1 locationNCT06586008