Phase 4 DED Clinical Trials

12 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 112 of 12 trials

Recruiting
Phase 4

The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function

Dry Eye Disease (DED)
Southern California College of Optometry at Marshall B. Ketchum University30 enrolled1 locationNCT06655441
Recruiting
Phase 4

SYSTANE® PRO vs. MIEBO™ in Dry Eye Disease

Dry Eye Disease (DED)
Indiana University260 enrolled4 locationsNCT07243275
Recruiting
Phase 4

A Non-interventional Study to Evaluate the Anti-inflammatory Effects and the Clinical Efficacy of Topical Water Free Cyclosporin 0.1% Eye Drops in Patients With Dry Eye Disease and Associated Ocular Surface Inflammation Non-responding to Artificial Tears: the FOCUS Study

Dry Eye Disease (DED)
Medical University of Vienna25 enrolled1 locationNCT07463950
Recruiting
Phase 4

Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye

Juvenile Open Angle GlaucomaDry Eye Disease (DED)Interleukin 6+2 more
Universiti Sains Malaysia60 enrolled4 locationsNCT07396441
Recruiting
Phase 4

Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery

US-Guided Supraclavicular BlockInterscalene AnalgesiaTourniquet Pain+1 more
Al-Azhar University60 enrolled1 locationNCT05602636
Recruiting
Phase 4

New Preservative-free Combination of Trehalose, Sodium Hyaluronate and N-acetyl-aspartyl-glutamate (NAAGA) in Dry Eye

Dry Eye Disease (DED)
Laboratoires Thea30 enrolled1 locationNCT06903741
Not Yet Recruiting
Phase 4

Evaluating the effect of amoxicillin dosage and timing of administration on postoperative complications after retained lower third molar extraction: A double-blind randomized controlled clinical trial

pain and inflammation in the extraction of included third molars
Universidad de Granada100 enrolled1 locationACTRN12624001414505
Completed
Phase 4

Rectal and urethral flora in patients undergoing transrectal ultrasound guided prostate biopsy: clinical implications.

Infectious complications of transrectal ultrasound guided prostate biopsyProstatitis
Sotirios Gatsos200 enrolled1 locationACTRN12622000149763
Not Yet Recruiting
Phase 4

Comparison of Ultrasound Guided Saphenous Nerve Block using Two Different Anatomical Approaches in patients undergoing knee surgery

ultrasound guided nerve blocklower extremity surgeryanesthesia and analgesia
Levent Sahin60 enrolled1 locationACTRN12614000057684
Completed
Phase 4

Bispectral index-guided general anaesthesia in combination with interscalene block reduces desflurane consumption in arthroscopic shoulder surgery: a clinical comparison of bupivacaine versus levobupivacaine

Patients who had rotator cuff tears or shoulder instability or calcific tendonitis tendinitis were included in this prospective, randomized, double-blind clinical trial.
Levent Ozturk60 enrolled1 locationACTRN12613000381785
Completed
Phase 4

Plasma ropivacaine concentrations after ultrasound-guided transversus abdominis plane block, with and without adrenaline, for gynaecologic surgery

Plasma ropivacaine concentrations after ultrasound-guided transversus abdominis plane block, with and without adrenaline added.
A/Prof John Loadsman20 enrolled1 locationACTRN12612000842864
Terminated
Phase 4

Wellness Study

Chronic illness - patients who are generally unwell for an extended period.
Mood Research Foundation (WA)50 enrolled1 locationACTRN12608000398303