Degeneration Clinical Trials in Boston, Massachusetts
24 recruitingBoston, Massachusetts
Showing 1–20 of 24 trials
Recruiting
Phase 2
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Geographic AtrophyMacular Degeneration
Janssen Research & Development, LLC274 enrolled104 locationsNCT06635148
Recruiting
Phase 2
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Geographic Atrophy secondary to Age Related Macular Degeneration
Novartis Pharmaceuticals272 enrolled14 locationsNCT07441642
Recruiting
Phase 3
Extension Study for the Port Delivery System With Ranibizumab (Portal)
Neovascular Age-related Macular Degeneration
Hoffmann-La Roche1,000 enrolled165 locationsNCT03683251
Recruiting
Phase 3
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
wet age related macular degenerationAMDnAMD+3 more
AbbVie714 enrolled181 locationsNCT05407636
Recruiting
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
Retinitis PigmentosaInherited Retinal Degeneration
Jaeb Center for Health Research1,500 enrolled36 locationsNCT05589714
Recruiting
Phase 1
Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease
SARS CoV-2NeurodegenerationReproductive Disorder
Stephanie B. Seminara, MD40 enrolled1 locationNCT07224490
Recruiting
Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH)
Stargardt DiseaseStargardt Disease 1Cone-Rod Dystrophy+1 more
Ascidian Therapeutics, Inc50 enrolled8 locationsNCT06445322
Recruiting
Not Applicable
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
Complex Congenital Heart DefectDysfunctional RVOT ConduitPulmonary Valve Insufficiency+1 more
Edwards Lifesciences108 enrolled25 locationsNCT02744677
Recruiting
Phase 1Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
Neovascular (Wet) Age-related Macular Degeneration
4D Molecular Therapeutics215 enrolled25 locationsNCT05197270
Recruiting
Phase 3
Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD
Neovascular Age-related Macular Degeneration
Jaeb Center for Health Research600 enrolled64 locationsNCT05904028
Recruiting
Phase 2
Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD
Age-Related Macular Degeneration
Massachusetts Eye and Ear Infirmary21 enrolled1 locationNCT04735263
Recruiting
Phase 1
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Age-Related Macular Degeneration
Astellas Institute for Regenerative Medicine42 enrolled19 locationsNCT03178149
Recruiting
The CurePSP Genetics Program
Multiple System Atrophy, Parkinsonian TypeMultiple System Atrophy, Cerebellar TypeMultiple System Atrophy+15 more
Massachusetts General Hospital1,000 enrolled1 locationNCT06647641
Recruiting
Phase 1Phase 2
Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)
Stargardt DiseaseStargardt Disease 1Cone-Rod Dystrophy+1 more
Ascidian Therapeutics, Inc15 enrolled10 locationsNCT06467344
Recruiting
Phase 1Phase 2
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration
Neovascular Age-related Macular Degeneration
Sanofi66 enrolled18 locationsNCT06660667
Recruiting
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
Lung CancerCancer RiskCancer Predisposition Syndrome+28 more
Dana-Farber Cancer Institute5,000 enrolled1 locationNCT05463796
Recruiting
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Amyotrophic Lateral SclerosisCorticobasal Degeneration (CBD)Progressive Supranuclear Palsy (PSP)+11 more
Mayo Clinic2,100 enrolled27 locationsNCT04363684
Recruiting
Gait Analysis in Neurological Disease
Multiple System AtrophyHuntington DiseaseCorticobasal Degeneration+5 more
Beth Israel Deaconess Medical Center120 enrolled1 locationNCT02994719
Recruiting
Phase 1Phase 2
Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Neovascular Age-related Macular Degeneration
Skyline Therapeutics (US) Inc.68 enrolled9 locationsNCT05986864
Recruiting
Phase 1
The HALT Biomarker Study
Aortic StenosisHypo-attenuated Leaflet ThickeningBioprosthetic Valve Degeneration
Massachusetts General Hospital300 enrolled3 locationsNCT04552275