Dental Clinical Trials

284 recruitingLast updated: May 13, 2026

There are 284 actively recruiting dental clinical trials across 54 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 1, Phase 3, Early Phase 1. Top locations include Cairo, Egypt, Paris, France, Cairo, Cairo Governorate, Egypt. Updated daily from ClinicalTrials.gov.


Dental Trials at a Glance

284 actively recruiting trials for dental are listed on ClinicalTrialsFinder across 6 cities in 54 countries. The largest study group is Not Applicable with 200 trials, with the heaviest enrollment activity in Cairo, Paris, and Cairo. Lead sponsors running dental studies include Cairo University, Ain Shams University, and Mansoura University.

Treatments under study

About Dental Clinical Trials

Looking for clinical trials for Dental? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dental trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dental clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 284 trials

Recruiting

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

Dental Diseases
University Hospital, Toulouse120 enrolled9 locationsNCT06506734
Recruiting
Not Applicable

Dental Implant Healing With TNF-Alpha Inhibitors

Dental ImplantsEdentulismTNF-alpha Inhibitors
University of Pennsylvania30 enrolled1 locationNCT06538870
Recruiting
Not Applicable

Evaluation of Zygomatic Implant Placement Accuracy Using Fully Metallic vs Resin-based Static Surgical Guides in Severely Atrophic Maxilla

Dental ImplantZygomatic ImplantsAtrophic Edentulous Maxilla+2 more
Future University in Egypt4 enrolled1 locationNCT07551024
Recruiting
Not Applicable

Assessment of Soft Tissue Thickness Over Zygomatic Implants in Atrophied Maxilla Covered With Buccal Fat Pad vs. Palatal Pedicle Flap

Dental ImplantSoft Tissue Augmentation at Dental ImplantsZygomatic Implants+5 more
Future University in Egypt4 enrolled1 locationNCT07574606
Recruiting
Not Applicable

Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment

Dental malocclusionMaxillary Deficiency
Universidad Complutense de Madrid40 enrolled1 locationNCT06315348
Recruiting

Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.

Dental Restoration, PermanentEndodontic TreatmentDental Restorations
Septodont275 enrolled8 locationsNCT06955429
Recruiting
Not Applicable

Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem

Gingival bleedingGingival inflammationDental Plaque
Unilever R&D150 enrolled1 locationNCT07415733
Recruiting

Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior

Endosseous Dental Implant FailureAccident Caused by Broken Ceramic
Implantology Institute90 enrolled1 locationNCT01974362
Recruiting
Not Applicable

Assessment of Digital Technologies for Detection of Dental Caries

Dental Caries
University Hospital, Martin100 enrolled1 locationNCT07560514
Recruiting
Phase 2Phase 3

Naltrexone for Overdose Prevention

Overdose Accidental
University of California, San Francisco100 enrolled1 locationNCT06633900
Recruiting
Not Applicable

Assessment of Soft Tissue Thickness Following Utilization of Buccal Pad of Fat Versus Platelet-rich Fibrin for Covering Zygomatic Implants: A Randomized Clinical Trial

Soft Tissue Augmentation at Dental Implants
Cairo University24 enrolled1 locationNCT07562334
Recruiting

Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries

Dental PlaqueDental Caries
University Ghent50 enrolled1 locationNCT07555223
Recruiting
Not Applicable

Aromatherapy vs Music Therapy for Anxiety in Children During Dental Radiography

Dental Anxiety in ChildrenPediatric Anxiety
Nigde Omer Halisdemir University100 enrolled1 locationNCT07542665
Recruiting
Not Applicable

Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA

Dental Implant
Barts & The London NHS Trust39 enrolled1 locationNCT06086873
Recruiting
Not Applicable

Home Treatment of Patients With Active Cancer and Acute Pulmonary Embolism Without HESTIA Criteria.

Active Cancer and Symptomatic or Incidental Pulmonary Embolism Without HESTIA Criteria
Assistance Publique - Hôpitaux de Paris824 enrolled20 locationsNCT07315347
Recruiting
Not Applicable

Clinical Performance of Bioactive Bulk-Fill in Class II Restorations

Dental Caries
Bezmialem Vakif University34 enrolled1 locationNCT07547904
Recruiting
Not Applicable

Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children

PainTooth ExtractionDental Anxiety
Arzu Pınar Erdem132 enrolled1 locationNCT07547371
Recruiting
Not Applicable

Vestibular Socket Therapy Using Magnesium Membrane Versus Cortical Lamina for Immediate Implant Placement in Type II Extraction Sockets

Immediate Dental Implant in Type 2 Extraction SocketVestibular Socket Therapy
Mohamed Adel Alfeky24 enrolled1 locationNCT07526272
Recruiting
Not Applicable

Comparative Study of Caries-Preventive Effects: 2% Calcium Hypophosphite Toothpaste vs. Sodium Fluoride Toothpaste (1450ppm F)

Caries,DentalCalcium HypophosphiteFluoridation
Dr. Joachim Enax164 enrolled2 locationsNCT07068204
Recruiting
Not Applicable

Mothers' Action Project for Child Health

Dental CariesObesity Risk
University of Massachusetts, Worcester460 enrolled1 locationNCT06753669