Dental Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Dental clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 247 trials

Recruiting
Not Applicable

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM

Dental CariesDental Restoration, PermanentTooth Diseases
Cukurova University12 enrolled1 locationNCT07031856
Recruiting
Not Applicable

Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study

Pulp Exposure, DentalDeep Dental Caries
Cukurova University15 enrolled1 locationNCT07041905
Recruiting
Not Applicable

Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients

Dental Plaque and GingivitisOral Hygiene Reinforcement During Fixed Orthodontic Treatment
Kumeran A/L Mohan78 enrolled1 locationNCT07288853
Recruiting
Not Applicable

Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker

Reversible PulpitisPulp Disease, DentalPulpitis+1 more
Abeer Ghalib Abdul-khaliq60 enrolled1 locationNCT07452614
Recruiting
Not Applicable

Use of Augmented Reality Glasses and Noise-Cancelling Headphones to Reduce Dental Anxiety in Adult Patients

Music TherapyDental AnxietyOral Surgical Procedures
Medical University of Warsaw250 enrolled1 locationNCT07398898
Recruiting
Not Applicable

A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth

Dental CariesInsufficient Dental Filling
Ivoclar Vivadent AG70 enrolled2 locationsNCT07212660
Recruiting
Not Applicable

Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics

Dental CariesTooth DemineralizationStreptococcus Mutans+1 more
Cardenal Herrera University200 enrolled2 locationsNCT07244991
Recruiting
Not Applicable

Effect of Local Application of 1% Metformin Gel on Implant Stability and Peri-implant Bone Density: A Randomized Controlled Study

StabilityDental Implant
University of Baghdad34 enrolled1 locationNCT07497568
Recruiting

Association Between Lingual Retraction and Hemodynamic Changes in Patients Receiving Dental Treatment Under General Anesthesia

Hemodynamic ChangesTrigeminocardiac ReflexDental Procedures
Kırıkkale University85 enrolled1 locationNCT07240688
Recruiting
Not Applicable

Adhesive Cementation Materials and Techniques in Aesthetic Dentistry

Dental VeneersResin CementsOrofacial Esthetic Scale
Riga Stradins University60 enrolled1 locationNCT07491809
Recruiting

OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia

Postoperative ComplicationsObstructive Sleep Apnea of AdultObstructive Sleep Apnea Risk Management+1 more
Kırıkkale University240 enrolled2 locationsNCT06430957
Recruiting
Not Applicable

Development of Pressure Sensor Based Dementia and Fall Prevention Program for Older Adults

Dementia, MildAccidental FallsMild Cognitive Impairment
Sunmi Song205 enrolled1 locationNCT06664229
Recruiting
Not Applicable

To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.

Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
University of Alabama at Birmingham40 enrolled1 locationNCT07191262
Recruiting
Early Phase 1

Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash

Dental Diseases
Cairo University30 enrolled1 locationNCT03384537
Recruiting
Not Applicable

Toothbrushes in Daily Practice in Patients With Fixed Orthodontic Appliances

Dental Malposition
Claude Bernard University120 enrolled1 locationNCT05851963
Recruiting
Not Applicable

L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation

Dental Implant Failed
Kafrelsheikh University45 enrolled2 locationsNCT07433920
Recruiting
Not Applicable

Hard Tissue Augmentation With or Without Connective Tissue Graft in Immediate Esthetic Implants

Dental Implant
University of Baghdad28 enrolled1 locationNCT07333534
Recruiting
Not Applicable

The Effect of a Kaleidoscope and Cartoons for Dental Treatment in Children

PainDental AnxietyDental Fear
Dicle University126 enrolled1 locationNCT07462364
Recruiting
Not Applicable

Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis

Peri-implantitisSoft Tissue Augmentation at Dental Implants
Gazi University30 enrolled1 locationNCT07471386
Recruiting
Not Applicable

AI-Driven Digital Self-Assessment Framework for Preclinical Tooth Preparation

Dental Education
Alexandria University36 enrolled1 locationNCT07462156