Phase 4 Dependence Clinical Trials

15 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 115 of 15 trials

Recruiting
Phase 4

Beta-Adrenergic Modulation of Drug Cue Reactivity

Tobacco Use DisorderNicotine DependenceCigarette Smoking
University of Oklahoma80 enrolled1 locationNCT05587361
Recruiting
Phase 4

Smoking Cessation and Menstrual Cycle Phase

Smoking CessationSubstance Use DisordersNicotine Dependence+2 more
Centre for Addiction and Mental Health1,200 enrolled1 locationNCT05515354
Recruiting
Phase 4

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

Cocaine Use DisorderCrack Abuse or Dependence
University of Sao Paulo General Hospital36 enrolled1 locationNCT07313371
Recruiting
Phase 4

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

Tobacco Dependence
Johns Hopkins University30 enrolled1 locationNCT07220356
Recruiting
Phase 4

Enhancing Hypnotic Medication Discontinuation in Primary Care

InsomniaHypnotic Dependence
National Jewish Health430 enrolled1 locationNCT06435520
Recruiting
Phase 4

Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial

Tobacco Use DisorderPsychiatric DisorderNicotine Dependence
Centre for Addiction and Mental Health40 enrolled1 locationNCT06534047
Recruiting
Phase 4

Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

Tobacco DependenceTobacco Use CessationTobacco Use+2 more
University of California, San Francisco150 enrolled1 locationNCT07148232
Recruiting
Phase 4

Better Options for Chronic Cancer Pain

Chronic PainCancer SurvivorOpioid Dependence
VA Office of Research and Development294 enrolled2 locationsNCT06574009
Recruiting
Phase 4

Young Houston Emergency Opioid Engagement System

Opioid UseSubstance Use DisordersOpioid-use Disorder+2 more
The University of Texas Health Science Center, Houston250 enrolled1 locationNCT04811014
Recruiting
Phase 4

tDCS Plus Varenicline for Smoking Cessation

Smoking CessationTobacco Use DisorderSubstance Use Disorders+3 more
Centre for Addiction and Mental Health160 enrolled1 locationNCT06798324
Recruiting
Phase 4

E-cigarette Cessation in Adults Who Co-use Cannabis

Tobacco Use DisorderNicotine Dependence
Medical University of South Carolina105 enrolled3 locationsNCT06688539
Suspended
Phase 4

Impact of injection site on buprenorphine pharmacokinetics.

Opioid Dependence
Sydney Local Health District50 enrolled5 locationsACTRN12623000691640
Not Yet Recruiting
Phase 4

Addressing Smoking in Sheltered homeless with Intensive Smoking Treatment

Nicotine Dependence
The University of Newcastle20 enrolled1 locationACTRN12619001564145
Completed
Phase 4

Varenicline and nicotine replacement therapy for smokers admitted to hospitals

Nicotine Dependence
Monash University, Faculty of Pharmacy and Pharmaceutical Sciences, Centre for Medicine Use and Safety320 enrolled5 locationsACTRN12618001792213
Completed
Phase 3Phase 4

Optimising Management of acute pain in Opioid Substitution Therapy patients: A pilot laboratory randomised study

Acute pain in opioid dependence
Sydney Local Health District - Royal Prince Alfred Hospital36 enrolled1 locationACTRN12612000288820