Depressive Disorder Clinical Trials in Philadelphia, Pennsylvania

17 recruitingPhiladelphia, Pennsylvania

Showing 117 of 17 trials

Recruiting
Phase 3

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

DepressionDepression - Major Depressive DisorderDepression in Adults+3 more
Cybin IRL Limited330 enrolled67 locationsNCT06793397
Recruiting
Phase 3

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder
Neurocrine Biosciences850 enrolled87 locationsNCT06966401
Recruiting
Early Phase 1

Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

Major Depressive Disorder (MDD)
University of Pennsylvania10 enrolled1 locationNCT06788249
Recruiting
Phase 2

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Major Depressive Disorder
Syndeio Biosciences, Inc164 enrolled32 locationsNCT07115329
Recruiting
Phase 3

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder
Neurocrine Biosciences200 enrolled30 locationsNCT06963021
Recruiting
Phase 2

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

Depressive Disorder, Major
Janssen Research & Development, LLC124 enrolled44 locationsNCT06785012
Recruiting

A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)

Depressive Disorder, Major
Janssen Research & Development, LLC80 enrolled23 locationsNCT07258485
Recruiting
Phase 3

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Depressive Disorder, Major
Janssen Research & Development, LLC752 enrolled205 locationsNCT06559306
Recruiting
Phase 3

Study to Assess the Safety and Effectiveness of NMRA-335140-501

Major Depressive Disorder
Neumora Therapeutics, Inc.1,000 enrolled178 locationsNCT06029439
Recruiting
Phase 2

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled40 locationsNCT06705478
Recruiting
Phase 3

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

Depressive Disorder, Major
Eli Lilly and Company1,000 enrolled186 locationsNCT07412756
Recruiting
Phase 3

Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

Major Depressive Disorder
Neumora Therapeutics, Inc.332 enrolled74 locationsNCT06058013
Recruiting
Not Applicable

Taking Action for College Students

SchizophreniaMajor Depressive DisorderBipolar Disorder
Temple University300 enrolled1 locationNCT06700902
Recruiting
Not Applicable

Neurofeedback to Treat Depression - 2

Major Depressive Disorder (MDD)
University of Pennsylvania80 enrolled1 locationNCT07159061
Recruiting
Not Applicable

Decoding and Modulating Affective Brain States

AnxietyMajor Depressive DisorderRumination
University of Pennsylvania40 enrolled1 locationNCT05437705
Recruiting
Phase 3

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Major Depressive Disorder
Intra-Cellular Therapies, Inc.470 enrolled60 locationsNCT05850689
Recruiting
Not Applicable

Getting Out of the House: Using Behavioral Activation to Increase Community Participation

SchizophreniaMajor Depressive DisorderBipolar Disorder+1 more
Temple University52 enrolled1 locationNCT06336616