Phase 1 Diabetes Mellitus, Type 1 Clinical Trials

12 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 112 of 12 trials

Recruiting
Phase 1

Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells

Diabetes Mellitus, Type 1
Medical University of South Carolina60 enrolled1 locationNCT04061746
Recruiting
Phase 1

A Study of LY4057996 in Healthy Participants and Participants With Type 1 and Type 2 Diabetes

Diabetes Mellitus, Type 2Diabetes Mellitus, Type 1
Eli Lilly and Company124 enrolled1 locationNCT06945406
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 1Phase 2

Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes

Diabetes Mellitus, Type 1
City of Hope Medical Center20 enrolled1 locationNCT03746769
Recruiting
Phase 1Phase 2

Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes

Diabetes Mellitus, Type 1Type 1 Diabetes
Creative Medical Technology Holdings Inc18 enrolled1 locationNCT05626712
Recruiting
Phase 1

A Research Study of a New Medicine NNC0363-1063 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1
Novo Nordisk A/S36 enrolled1 locationNCT07305805
Recruiting
Phase 1

Subcutaneous Pharmacokinetic Evaluation of Monomeric Insulin and Lyumjev in Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1Type 1 Diabetes Mellitus
Stanford University20 enrolled1 locationNCT07090824
Recruiting
Phase 1

A Research Study of a New Medicine NNC0363-1063 in Healthy Participants and Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1
Novo Nordisk A/S154 enrolled1 locationNCT06685185
Recruiting
Phase 1

Phase I Clinical Study to Evaluate the Safety and Efficacy of RGB-5088 in Patients With Type 1 Diabetes Mellitus

Diabetes MellitusDiabetes Mellitus, Type 1
Hangzhou Reprogenix Bioscience, Inc10 enrolled1 locationNCT06731218
Recruiting
Phase 1Phase 2

A Safety, Tolerability, and Efficacy Study of E-islet 01 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
EndoCell Therapeutics, Inc.21 enrolled1 locationNCT07126873
Recruiting
Phase 1

A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 Diabetes

Diabetes Mellitus, Type 1
Novo Nordisk A/S96 enrolled1 locationNCT07087795
Recruiting
Phase 1Phase 2

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

Diabetes MellitusMetabolic DiseaseDiabetes Mellitus, Type 1+4 more
CRISPR Therapeutics AG40 enrolled2 locationsNCT05565248