Phase I Clinical Study to Evaluate the Safety and Efficacy of RGB-5088 in Patients With Type 1 Diabetes Mellitus

This Phase I study is testing a new treatment called RGB-5088 in people with Type 1 diabetes to see if it is safe and whether it helps preserve or restore the body's ability to produce insulin. **You may be eligible if...** - You are 18–60 years old - You have confirmed Type 1 diabetes (including those who have had a liver or kidney transplant) - Your C-peptide level (a marker of insulin production) is very low - You have had at least one severe low blood sugar episode in the past 12 months **You may NOT be eligible if...** - You have Type 2 diabetes - You have untreated diabetic eye disease (proliferative retinopathy) - You have serious heart disease, severe gut problems, or serious mental health conditions - You have any history of cancer - You have a history of tobacco, alcohol, or drug abuse - You are pregnant, breastfeeding, or unwilling to use contraception Talk to your doctor to see if this trial is right for you.