Disc Degeneration Clinical Trials

5 recruiting

Disc Degeneration Trials at a Glance

11 actively recruiting trials for disc degeneration are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Broadmeadow, Charleston, and Clayton. Lead sponsors running disc degeneration studies include VIVEX Biologics, Inc., Marmara University, and Copernicus Memorial Hospital.

Browse disc degeneration trials by phase

Treatments under study

About Disc Degeneration Clinical Trials

Looking for clinical trials for Disc Degeneration? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Disc Degeneration trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Disc Degeneration clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

Degenerative Disc DiseaseDisc DegenerationLumbar Discogenic Pain
VIVEX Biologics, Inc.496 enrolled19 locationsNCT06778447
Recruiting
Not Applicable

Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain

Lumbar Disc DegenerationLumbar Degenerative DiseaseLower Back Pain Chronic
Copernicus Memorial Hospital100 enrolled1 locationNCT07127380
Recruiting

Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery

Lumbar Spinal StenosisLumbar Disc Herniation With RadiculopathyLumbar Degenerative Spondylolisthesis+1 more
Marmara University75 enrolled1 locationNCT07489001
Recruiting
Not Applicable

Comparaison of Interbody Bone Fusion Between Two Osteoinductive Bioactive Bone Substitutes After Anterior Lumbar Interbody Arthrodesis in Degenerative Lumbar Disc Surgery in Adults

Disc Degeneration
University Hospital, Montpellier100 enrolled1 locationNCT07044206
Recruiting
Not Applicable

Cervical Movement Control Before and After Anterior Cervical Discectomy and Fusion

Cervical Vertebral Disc Degeneration
University of Ljubljana30 enrolled1 locationNCT07425613
Recruiting
Phase 4

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF

SurgeryDisc DegenerationDisc Disease+2 more
Potsawat Surabotsopon60 enrolled1 locationNCT06367855
Recruiting

The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease

Low Back PainLumbar Disc HerniationLumbar Disc Degeneration+1 more
Masaryk University400 enrolled1 locationNCT07085247
Recruiting

Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement

SciaticaLumbar Disc HerniationLumbar Disc Degeneration+2 more
University of Valencia150 enrolled1 locationNCT06989632
Recruiting
Not Applicable

Pilot Study of ZetaFuse™ Bone Graft for the Treatment of Cervical Degenerative Disc Disease

Disc DegenerationDisc DiseaseNeurological Abnormality+2 more
Zetagen Therapeutics, Inc10 enrolled2 locationsNCT05971329
Recruiting
Phase 2

ASCEND: A Clinical Trial to Evaluate the Safety and Effectiveness of VIA Disc NP, a Supplement for Degenerated Intervertebral Discs

Degenerative Disc DiseaseDisc DegenerationLumbar Discogenic Pain
VIVEX Biologics, Inc.110 enrolled5 locationsNCT06615505
Recruiting

Lumbar microdiscectomy and post-operative activity restrictions

Lumbar Intervertebral Disc Degeneration
Assoc. Prof. Tony Goldschlager120 enrolled3 locationsACTRN12616001360404