Phase 2 Disease Clinical Trials
935 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 935 trials
Recruiting
Phase 2Phase 3
ACP-204 in Adults With Alzheimer's Disease Psychosis
Alzheimer's Disease Psychosis
ACADIA Pharmaceuticals Inc.1,074 enrolled148 locationsNCT06159673
Recruiting
Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting
Phase 2
Autologous Stem Cell Transplant for Crohn's Disease
Crohn Disease
Aaron Etra50 enrolled1 locationNCT03219359
Recruiting
Phase 2
Motixafortide for MRD Sensitization in AML
Measurable Residual DiseaseAcute Myeloid Leukemia
Washington University School of Medicine10 enrolled1 locationNCT07392970
Recruiting
Phase 2
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Psychosis Associated With Alzheimer's Disease
Intra-Cellular Therapies, Inc.370 enrolled65 locationsNCT06540833
Recruiting
Phase 2
Bioenergetic Effect of Pioglitazone in CLD-PH
Pulmonary HypertensionPulmonary Hypertension Due to Lung Diseases
Emory University20 enrolled1 locationNCT06336798
Recruiting
Phase 2
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled22 locationsNCT07326566
Recruiting
Phase 2
Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease
Sickle Cell Disease
St. Jude Children's Research Hospital45 enrolled1 locationNCT07616154
Recruiting
Phase 2
Tirzepatide in MetALD
Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2
A Study of Luspatercept in People With Anemia
Chronic Kidney DiseaseAnemia
Memorial Sloan Kettering Cancer Center30 enrolled7 locationsNCT07725497
Recruiting
Phase 2
Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
Parkinson Disease
Gateway Institute for Brain Research56 enrolled4 locationsNCT05266417
Recruiting
Phase 2
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
ObesityBody WeightOverweight+5 more
Pfizer872 enrolled65 locationsNCT07575932
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety and Effectiveness of Withaferin A as a Treatment to Prevent GvHD in Transplant Patients
Hematopoietic Stem Cell Transplant (HSCT)Hematological MalignancyGVHD - Graft-Versus-Host Disease
Tata Memorial Centre54 enrolled2 locationsNCT07724873
Recruiting
Phase 2Phase 3
Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of VG081821AC Tablets in Patients With Early to Mid-stage Parkinson's Disease
Parkinson Disease (PD)
Zhejiang Vimgreen Pharmaceuticals, Ltd.152 enrolled1 locationNCT07725562
Recruiting
Phase 2
A Trial to Assess the Efficacy and Safety of Obinutuzumab in Treating Adults With Minimal Change Disease (MCD)
Minimal Change Disease (MCD)
Medical University Innsbruck48 enrolled6 locationsNCT07710157
Recruiting
Phase 2Phase 3
A Study of Buntanetap in Participants With PD
Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 2
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
StrokeParkinson DiseaseDysphagia
Purdue University120 enrolled2 locationsNCT06638944
Recruiting
Phase 1Phase 2
REGEND001 Autologous Basal Layer Stem Cell Transplantation for Chronic Obstructive Pulmonary Disease (COPD): A Translational Application Study
Chronic Obstructive Pulmonary Disease (COPD)
Ruijin Hospital20 enrolled2 locationsNCT06946953
Recruiting
Phase 1Phase 2
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Sickle Cell Disease
Novartis Pharmaceuticals161 enrolled9 locationsNCT06546670
Recruiting
Phase 2
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
End Stage Renal Disease on DialysisHyperphosphatemiaChronic Kidney Disease Requiring Chronic Dialysis
R1 Therapeutics168 enrolled31 locationsNCT06712654