Phase 4 Diseases Clinical Trials

79 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 79 trials

Recruiting
Phase 4

Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

Parkinson DiseaseNeurodegenerative DiseasesParkinson Disease Psychosis
Vanderbilt University Medical Center75 enrolled1 locationNCT05357612
Recruiting
Phase 4

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Genetic PredispositionType 2 DiabetesMetabolic Diseases
Massachusetts General Hospital125 enrolled1 locationNCT06003153
Recruiting
Phase 4

Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement

ThromboembolismAORTIC VALVE DISEASES
Joon Bum Kim1,300 enrolled16 locationsNCT04258488
Recruiting
Phase 4

ASpirin Use and stAtin Strategy for Primary Prevention in Severe Coronary Calcium Score on Computed Tomography

Cardiovascular Diseases
Jung-min Ahn5,000 enrolled32 locationsNCT06676280
Recruiting
Phase 4

Comparison of the Effects of Belatacept and Anticalcineurins on Endothelial Function in Renal Transplant Patients - <BELAFENDO>

Kidney Diseases
University Hospital, Rouen44 enrolled1 locationNCT06291077
Recruiting
Phase 4

Treatment With Aspirin After Preeclampsia: TAP Trial

Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Cardiovascular DiseasesDementiaCognitive Impairment, Mild
Duke University20,000 enrolled103 locationsNCT04262206
Recruiting
Phase 4

Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism

Cardiovascular DiseasesVenous ThromboembolismPulmonary Embolism+6 more
Drahomir Aujesky276 enrolled40 locationsNCT04263038
Recruiting
Phase 4

Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)

Psoriatic Arthritis (PsA)AtherosclerosisRheumatoid Arthritis (RA)+4 more
Instituto de Investigación Marqués de Valdecilla1,944 enrolled17 locationsNCT07611747
Recruiting
Phase 4

Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome

Pathologic ProcessesIntestinal DiseaseGastrointestinal Diseases+5 more
EP Plus Group Sdn Bhd60 enrolled1 locationNCT06271538
Recruiting
Phase 4

The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine

Hepatocellular Carcinoma (HCC)Liver Diseases
Anhui Provincial Hospital96 enrolled1 locationNCT07150624
Recruiting
Phase 4

Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation

Chronic Kidney Diseases
University of Erlangen-Nürnberg Medical School48 enrolled1 locationNCT06560801
Recruiting
Phase 4

Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies

AntibioticsPeriodontal DiseasesPharmacokinetics
University of Geneva, Switzerland45 enrolled1 locationNCT04669717
Recruiting
Phase 4

Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery

Thyroid Diseases
Bach Mai Hospital100 enrolled1 locationNCT07462195
Recruiting
Phase 4

Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE

Cardiovascular DiseasesInflammatory ResponseAcute Myocardial Infarction
Region Örebro County90 enrolled3 locationsNCT06336317
Recruiting
Phase 4

The Leadless AV Versus DDD Pacing Study

Cardiovascular DiseasesArrhythmias, CardiacHeart Diseases+1 more
Insel Gruppe AG, University Hospital Bern100 enrolled1 locationNCT05498376
Recruiting
Phase 4

Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease

Genital Diseases, MaleSexual Dysfunctions, PsychologicalPeyronie Disease
University of Miami22 enrolled2 locationsNCT05777031
Recruiting
Phase 4

Intrapleural Ropivacaine Infusion in Cardiac Surgery

Coronary Artery DiseaseCardiac SurgeryValvular Diseases
Saint Petersburg State University, Russia116 enrolled2 locationsNCT07116343
Recruiting
Phase 4

Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases Under Immunomodulators

Autoimmune Rheumatic Diseases
University of Sao Paulo General Hospital200 enrolled1 locationNCT07280741
Recruiting
Phase 4

Erector Spinae Block for Thoracic Surgery

Thoracic CancerPulmonary CancerThoracic Neoplasms+2 more
George Washington University70 enrolled1 locationNCT05521789