Phase 3 DLBCL Clinical Trials

8 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 18 of 8 trials

Recruiting
Phase 2Phase 3

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

DLBCL
Merck Sharp & Dohme LLC290 enrolled121 locationsNCT05139017
Recruiting
Phase 2Phase 3

NexCAR19 (Talikabtagene Autoleucel) in Relapsed/Refractory B-Cell Malignancies (NexCAR19)

Diffuse Large B-Cell Lymphoma (DLBCL)Follicular Lymphoma ( FL)Relapsed/Refractory Non-Hodgkin Lymphoma+2 more
Health Institutes of Turkey40 enrolled4 locationsNCT07502118
Recruiting
Phase 3

Chidamide for Maintenance Treatment of HBV-infected Diffuse DLBCL in Patients Initially Treated With R-CHOP

Diffuse Large B-Cell Lymphoma (DLBCL)
Ou Bai, MD/PHD200 enrolled1 locationNCT07493109
Recruiting
Phase 3

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma

DLBCL - Diffuse Large B Cell Lymphoma
Stichting Hemato-Oncologie voor Volwassenen Nederland324 enrolled25 locationsNCT06220032
Recruiting
Phase 2Phase 3

Xinlikang Capsule for Chemotherapy-induced Fatigue and Immune Disorders in Diffuse Large B Lymphoma

Diffuse Large B-Cell Lymphoma (DLBCL)
Sun Yat-sen University80 enrolled1 locationNCT07084662
Recruiting
Phase 3

A Randomized, Multicenter, Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma

Diffuse Large B Cell LymphomaDLBCL
Nordic Lymphoma Group300 enrolled69 locationsNCT04332822
Recruiting
Phase 3

Evaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

DLBCL
Beijing InnoCare Pharma Tech Co., Ltd.244 enrolled20 locationsNCT06521255
Active
Phase 3

Study of Lenalidomide Maintenance Versus Placebo in Responding Elderly Patients With Diffuse Large B cell Lymphoma (DLBCL) and Treated With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP)

Diffuse large B cell lymphoma (DLBCL) in elderly patients
Australasian Leukaemia and Lymphoma Group80 enrolled3 locationsACTRN12611000085976