Dysfunction Clinical Trials in Aurora, Colorado

17 recruitingAurora, Colorado

Showing 117 of 17 trials

Recruiting
Phase 2

Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH

MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc.120 enrolled17 locationsNCT07335601
Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Phase 3

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer117 enrolled132 locationsNCT07192952
Recruiting
Phase 3

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

MASH - Metabolic Dysfunction-Associated SteatohepatitisNASH - Nonalcoholic Steatohepatitis
Akero Therapeutics, Inc2,150 enrolled322 locationsNCT06528314
Recruiting
Phase 3

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company4,500 enrolled561 locationsNCT07165028
Recruiting
Phase 2Phase 3

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled106 locationsNCT05714085
Recruiting
Phase 2

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

Metabolic dysfunction-associated steatohepatitis (MASH)
Regeneron Pharmaceuticals120 enrolled71 locationsNCT05519475
Recruiting
Not Applicable

Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease

ExerciseExercise TrainingCOPD+2 more
University of Colorado, Denver60 enrolled1 locationNCT07576894
Recruiting
Not Applicable

Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

ExerciseExercise TrainingCOPD+2 more
University of Colorado, Denver60 enrolled1 locationNCT05896579
Recruiting
Phase 3

Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome

Autonomic DysfunctionDown Syndrome
University of Colorado, Denver200 enrolled1 locationNCT07238465
Recruiting
Phase 2Phase 3

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Nationwide Children's Hospital500 enrolled32 locationsNCT05267821
Recruiting
Not Applicable

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

Complex Congenital Heart DefectDysfunctional RVOT ConduitPulmonary Valve Insufficiency+1 more
Edwards Lifesciences108 enrolled25 locationsNCT02744677
Recruiting

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Survivors of Childhood CancerBladder Dysfunction
University of Colorado, Denver152 enrolled1 locationNCT04993859
Recruiting
Not Applicable

NightWare and Cardiovascular Health in Veterans With PTSD

Autonomic DysfunctionCardiovascular DiseasesEndothelial Dysfunction+4 more
VA Office of Research and Development125 enrolled1 locationNCT06419959
Recruiting
Phase 1

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Cardiovascular DiseasesEndothelial DysfunctionType 1 Diabetes+2 more
Kalie Tommerdahl60 enrolled2 locationsNCT05065372
Recruiting

Puberty Suppression and Cardiometabolic Health

Insulin Sensitivity/ResistanceEndothelial DysfunctionVascular Stiffness+1 more
University of Colorado, Denver30 enrolled1 locationNCT04482374
Recruiting

Optimizing Pulsatility During Cardiopulmonary Bypass

Acute Kidney InjuryEndothelial Dysfunction
University of Colorado, Denver66 enrolled1 locationNCT05344573