Optimizing Pulsatility During Cardiopulmonary Bypass
Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury: Prospective Observational Study
University of Colorado, Denver
66 participants
Jul 5, 2022
OBSERVATIONAL
Conditions
Summary
Cardiopulmonary bypass during cardiac surgery provides blood flow to the body during surgery but has adverse effects on different organs. Blood flow during cardiopulmonary bypass may be pulsatile or non-pulsatile, which may impact normal organ function after surgery. The study will collect data on the type of cardiopulmonary bypass used during surgery and organ function to determine if there is an association between the type of bypass and organ function.
Eligibility
Inclusion Criteria3
- Age 50 to 70
- Able to provide informed consent
- Scheduled for elective cardiac surgery with cardiopulmonary bypass
Exclusion Criteria8
- Patients undergoing emergency procedures
- Diagnosed with sepsis
- Experiencing delirium
- Experiencing hemodynamic instability (heart rate > 100 and systolic blood pressure < 90)
- Patients with a mechanical circulatory support device
- Requiring vasoactive medications before surgery
- Patients with a reduced left ventricular ejection fraction (less than 50%)
- Patients with a contraindication to transesophageal echocardiography
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05344573