Phase 2 Early Stage Breast Cancer Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 2

FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Yale University92 enrolled2 locationsNCT06917313
Recruiting
Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Breast CancerBreast NeoplasmHER2-negative Breast Cancer+7 more
Fudan University716 enrolled1 locationNCT05582499
Recruiting
Phase 2

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

Breast CancerBreast NeoplasmsHER2-negative Breast Cancer+8 more
QuantumLeap Healthcare Collaborative5,000 enrolled42 locationsNCT01042379
Recruiting
Phase 2

Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer

Breast CancerTriple Negative Breast Cancer(TNBC)Early Stage Breast Cancer+2 more
Sun Yat-sen University192 enrolled5 locationsNCT06768931
Recruiting
Phase 2

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

Breast CancerDuctal Carcinoma in SituEarly Stage Breast Cancer+1 more
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT06902311
Recruiting
Phase 2

Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer Patients

Breast CancerEarly Stage Breast CancerAdjuvant Treatment
Dartmouth-Hitchcock Medical Center62 enrolled1 locationNCT07071038
Recruiting
Phase 2Phase 3

Continuous Positive Airway Pressure (CPAP) Assisted Radiotherapy in Breast Cancer

Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Universitaire Ziekenhuizen KU Leuven53 enrolled1 locationNCT07373782
Recruiting
Phase 2

ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer

HER2-negative Breast CancerBreast Cancer Early Stage Breast Cancer (Stage 1-3)Hormone Receptor-Positive Breast Cancer+3 more
Peking University People's Hospital393 enrolled1 locationNCT06970912
Recruiting
Phase 2

BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer

Breast Cancer InvasiveHigh Risk Breast CarcinomaEarly Stage Breast Cancer
University of Illinois at Chicago40 enrolled1 locationNCT04891068
Recruiting
Phase 2

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

Early Stage Breast CancerCardiac Toxicity
Rutgers, The State University of New Jersey60 enrolled10 locationsNCT05559164
Recruiting
Phase 2

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Invasive Breast CancerStage III Breast CancerStage IIB Breast Cancer+4 more
Jonsson Comprehensive Cancer Center88 enrolled9 locationsNCT04553770
Recruiting
Phase 2

SHR-A1811 Plus Pertuzumab in the Neoadjuvant Treatment of HER2 Positive BC

Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Henan Cancer Hospital180 enrolled1 locationNCT06927180
Recruiting
Phase 2

Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)

Estrogen Receptor-positive Breast CancerEarly Stage Breast Cancer
Jules Bordet Institute112 enrolled1 locationNCT06150898
Recruiting
Phase 2

Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)

Early Stage Breast Cancer
German Cancer Research Center240 enrolled9 locationsNCT05332561
Recruiting
Phase 2

"The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients"

Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Ain Shams University80 enrolled1 locationNCT06679387