Phase 3 Edema Clinical Trials
28 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 28 trials
Recruiting
Phase 3
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
Hereditary AngioedemaHereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled51 locationsNCT06960213
Recruiting
Phase 3
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE)Hereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled48 locationsNCT07428499
Recruiting
Phase 3
Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks
Acute Hereditary Angio Edema
Octapharma124 enrolled21 locationsNCT06361537
Recruiting
Phase 3
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled65 locationsNCT07449936
Recruiting
Phase 3
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled62 locationsNCT07449923
Recruiting
Phase 3
Donidalorsen Treatment in Children With Hereditary Angioedema
Hereditary Angioedema (HAE)
Ionis Pharmaceuticals, Inc.20 enrolled10 locationsNCT07298447
Recruiting
Phase 3
AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction
Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Phase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
Macular Edema Secondary to Inflammation
Kodiak Sciences Inc300 enrolled56 locationsNCT06996080
Recruiting
Phase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Macular Edema Secondary to Inflammation
Kodiak Sciences Inc600 enrolled56 locationsNCT06990399
Recruiting
Phase 3
Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency
Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)
Pharvaris Netherlands B.V.32 enrolled17 locationsNCT07266805
Recruiting
Phase 3
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
Hereditary Angioedema (HAE)
Pharvaris Netherlands B.V.170 enrolled62 locationsNCT06679881
Recruiting
Phase 3
A Study of Navenibart in Participants With Hereditary Angioedema
Hereditary Angioedema (HAE)
Astria Therapeutics, Inc.145 enrolled87 locationsNCT06842823
Recruiting
Phase 3
Clinical Study to Compare Efficacy and Safety of AVT29 and Eylea HD in Participants With Diabetic Macular Edema
Diabetic Macular Edema
Alvotech Swiss AG256 enrolled1 locationNCT07489131
Not Yet Recruiting
Phase 3Phase 4
Dropless cataract surgery with a single subconjunctival triamcinolone injection versus topical steroid: a randomised controlled trial assessing effects on central macular thickness.
Steroid-induced glaucomaPost operative uveitisCystoid macular oedema
Bayside Health300 enrolled1 locationACTRN12626000516381
Recruiting
Phase 3
Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Diabetic Macular Edema
Diabetic Macular Edema (DME)
Bio-Thera Solutions406 enrolled50 locationsNCT07515079
Recruiting
Phase 3
A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME
Diabetic Macular Edema
Hoffmann-La Roche634 enrolled92 locationsNCT04108156
Recruiting
Phase 3
A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer
Breast CancerBreast CarcinomaLymphedema+3 more
Memorial Sloan Kettering Cancer Center285 enrolled7 locationsNCT06144164
Recruiting
Phase 3
Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns
Severe Diabetic Macular Oedema
Belfast Health and Social Care Trust264 enrolled22 locationsNCT06985706
Recruiting
Phase 2Phase 3
The Efficacy and Safety of HRS8179 in Severe Cerebral Edema Following Large Hemispheric Infarction
Severe Cerebral Edema Following Large Hemispheric Infarction
Beijing Suncadia Pharmaceuticals Co., Ltd725 enrolled1 locationNCT06732648
Recruiting
Phase 3
A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema
Retinal DegenerationMacular DegenerationDiabetic Retinopathy+3 more
Incepta Pharmaceuticals Ltd70 enrolled1 locationNCT06305416