Phase 2 Efficacy Clinical Trials

17 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 117 of 17 trials

Recruiting
Phase 1Phase 2

RIG 101 Trial in Healthy Adults and Adults With Asthma

healthy adult participantsSafety and EfficacyAsthma Exacerbation
RIGImmune Inc.82 enrolled2 locationsNCT07488897
Recruiting
Phase 2

Cognitive Remediation Intervention to Prepare for Transition of Care

Cognitive ImpairmentSickle Cell DiseaseSelf Efficacy+3 more
University of Alabama at Birmingham120 enrolled1 locationNCT05336201
Recruiting
Phase 1Phase 2

Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation

EfficacySafetyTolerability
Sichuan Huiyu Pharmaceutical Co., Ltd257 enrolled6 locationsNCT06243354
Recruiting
Phase 1Phase 2

Phase 1/2 Clinical Study of HY07121 Powder for Solution for Infusion in Patients With Advanced Solid Tumors

EfficacySafetyTolerability
Sichuan Huiyu Pharmaceutical Co., Ltd258 enrolled1 locationNCT06639256
Recruiting
Phase 1Phase 2

Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic Scars

hypertrophic scarsSafety and EfficacyTopical Administration+3 more
Herbarium Laboratorio Botanico Ltda80 enrolled2 locationsNCT06751433
Recruiting
Phase 2

Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal Cancer

Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal Cancer
Xinqiao Hospital of Chongqing96 enrolled1 locationNCT06279351
Recruiting
Phase 2

A Multicenter, Prospective, Cohort Study of Trop-2 ADC Combination Therapy for Advanced Triple-negative Breast Cancer

Evaluating the Efficacy of Trop-2 ADC Combination Therapy in Advanced Triple-Negative Breast Cancer
Tianjin Medical University Cancer Institute and Hospital138 enrolled1 locationNCT06878625
Recruiting
Phase 2

Promoting Active Therapy: Path to Wellness

Depression, AnxietyFeasibility Pilot StudyPhysical Activity+2 more
Kansas State University60 enrolled1 locationNCT06858189
Recruiting
Phase 1Phase 2

MSC Intratissular Injection in Crohn Disease Patients

Efficacy and Safety
University of Liege60 enrolled1 locationNCT03901235
Recruiting
Phase 1Phase 2

Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian Cancer

Efficacy and Safety
Xing Xie50 enrolled1 locationNCT04518501
Recruiting
Phase 2

Adebrelimab Combined With Chemotherapy and Concurrent SBRT for Neoadjuvant Treatment of Limited-stage Small Cell Lung Cancer

Efficacy and Safety of Neoadjuvant Immunotherapy for Small Cell Lung Cancer
Zhejiang Cancer Hospital20 enrolled1 locationNCT06562920
Recruiting
Phase 2

Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?

EfficacySafety Issues
Centre Hospitalier Universitaire de Liege50 enrolled1 locationNCT06317818
Active
Phase 2

FAB study: Fan, Activity and Breathlessness: assessing the fan’s capacity to increase physical activity in patients with breathlessness and reducing carer anxiety

Self-efficacy - care giversBreathlessness
The University of Notre Dame Australia,60 enrolled3 locationsACTRN12614000525684
Recruiting
Phase 2

Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors

Surgical ResectionThe Aim of the Study is to Evaluate the Efficacy of Photodynamic Therapy as anAdjuvant Therapy on the Clinical Outcome of Patients With Desmoid Tumors After
michal roll140 enrolled2 locationsNCT01898416
Completed
Phase 2

Efficacy of melatonin in rapid eye movement (REM sleep) behaviour disorder with coexisting Parkinsonism

REM sleep behaviour disorderEfficacy of melatoninParkinsonism
The Woolcock Institute of Medical Research30 enrolled1 locationACTRN12613000648729
Terminated
Phase 2

Efficacy of melatonin in idiopathic rapid eye movement (REM) sleep behaviour disorder

REM sleep behaviour disorderEfficacy of melatonin
The Woolcock Institute of Medical Research30 enrolled1 locationACTRN12613000647730
Not Yet Recruiting
Phase 2

Efficacy of Seasonal Influenza Vaccine (SIV) or “Flu vaccine” in cancer patients undergoing chemotherapy.

Efficacy of flu vaccine in cancer patient undergoing chemotherapy
Flinders Medical centre50 enrolled1 locationACTRN12611000306910