Phase 1 Endothelial Dysfunction Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1Phase 2
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans
Endothelial Dysfunction
Vanderbilt University Medical Center160 enrolled1 locationNCT04769206
Recruiting
Phase 1Phase 2
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 1Phase 2
TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVD
Endothelial DysfunctionAtherosclerotic Cardiovascular Diseases
Hudson Biotech80 enrolled1 locationNCT07487363
Recruiting
Phase 1Phase 2
Effect of a Daily Supplement on Plasma PAI-1 Levels
Endothelial DysfunctionAgingsenescence
University of California, Los Angeles35 enrolled2 locationsNCT07469475
Recruiting
Phase 1
PVEK Corneal Implant For Treatment of Corneal Edema
Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+1 more
Precise Bio15 enrolled3 locationsNCT07325097
Recruiting
Phase 1
Study to Assess Safety and Tolerability of Multiple Doses of EO2002
Endothelial DysfunctionPseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy+5 more
Asociación para Evitar la Ceguera en México12 enrolled1 locationNCT05636579
Recruiting
Phase 1
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Cardiovascular DiseasesEndothelial DysfunctionType 1 Diabetes+2 more
Kalie Tommerdahl60 enrolled2 locationsNCT05065372
Recruiting
Phase 1
B-Complex: A Nutraceutical SANS Countermeasure
optic disc edemaEndothelial Dysfunction
National Aeronautics and Space Administration (NASA)16 enrolled1 locationNCT05366933