Endothelial Dysfunction Clinical Trials

40 recruiting

Endothelial Dysfunction Trials at a Glance

41 actively recruiting trials for endothelial dysfunction are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 12 trials, with the heaviest enrollment activity in Iowa City, Aurora, and Englewood. Lead sponsors running endothelial dysfunction studies include Craig Hospital, University of Athens, and University of Colorado, Denver.

Browse endothelial dysfunction trials by phase

Treatments under study

About Endothelial Dysfunction Clinical Trials

Looking for clinical trials for Endothelial Dysfunction? There are currently 40 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Endothelial Dysfunction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Endothelial Dysfunction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 41 trials

Recruiting
Phase 1Phase 2

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Healthy VolunteersEndothelial DysfunctionInflammation in Cardiopulmonary and Vascular Disease States
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT03253705
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Not Applicable

Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal

Endothelial DysfunctionSleep Apnea, Obstructive
University Hospital, Angers40 enrolled1 locationNCT05939934
Recruiting
Phase 1Phase 2

TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVD

Endothelial DysfunctionAtherosclerotic Cardiovascular Diseases
Hudson Biotech80 enrolled1 locationNCT07487363
Recruiting
Phase 2

TRIal of STatin Therapy Effect on Androgen Status and Erectile functioN in Men

Erectile Dysfunction Due to Arterial DiseaseEndothelial DysfunctionErectile Disfunction+3 more
Lomonosov Moscow State University Medical Research and Educational Center150 enrolled1 locationNCT07460960
Recruiting
Phase 1Phase 2

Effect of a Daily Supplement on Plasma PAI-1 Levels

Endothelial DysfunctionAging
University of California, Los Angeles35 enrolled2 locationsNCT07469475
Recruiting

The Effect of Lipoprotein (a) on Arterial Stiffness, Endothelial Function and Myocardial Deformation

Arterial StiffnessEndothelial DysfunctionLipoprotein Disorder
University of Athens300 enrolled2 locationsNCT07324902
Recruiting
Phase 4

Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation

Endothelial DysfunctionIschemic StrokeCerebrovascular Event+4 more
Duan Chuanzhi354 enrolled1 locationNCT06308952
Recruiting

Perioperative Outcomes After Neoadjuvant Therapy in Colorectal Cancer

Neoadjuvant TherapyColorectal Carcinoma (CRC)Complications+1 more
Osijek University Hospital68 enrolled1 locationNCT07422974
Recruiting
Not Applicable

EndoPAT Device for Endothelial Dysfunction in ED

Hypogonadism, MaleErectile DysfunctionEndothelial Dysfunction
University of California, Irvine120 enrolled1 locationNCT06720597
Recruiting
Not Applicable

Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

HypertensionBlood PressureEndothelial Dysfunction+1 more
University of Colorado, Boulder90 enrolled1 locationNCT05000515
Recruiting
Phase 1

PVEK Corneal Implant For Treatment of Corneal Edema

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+1 more
Precise Bio15 enrolled3 locationsNCT07325097
Recruiting
Early Phase 1

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

Endothelial DysfunctionInflammationElectronic Cigarette Use
University of Iowa24 enrolled2 locationsNCT06489249
Recruiting
Early Phase 1

Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

Physical InactivityEndothelial DysfunctionGestational Diabetes
Anna Stanhewicz, PhD40 enrolled1 locationNCT06547619
Recruiting
Not Applicable

Microvascular Dysfunction in Obesity

ObesityEndothelial Dysfunction
Florida State University25 enrolled1 locationNCT04087655
Recruiting
Not Applicable

The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

SleepSleep DisturbanceEndothelial Dysfunction+6 more
Nathaniel Jenkins70 enrolled1 locationNCT06454344
Recruiting
Phase 1

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

Endothelial DysfunctionPseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy+5 more
Asociación para Evitar la Ceguera en México12 enrolled1 locationNCT05636579
Recruiting

Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury

Testosterone DeficiencyEndothelial DysfunctionSpinal Cord Injuries
Craig Hospital48 enrolled1 locationNCT07227740
Recruiting

Endothelial Dysfunction After SCI

Endothelial DysfunctionSpinal Cord Injuries
Craig Hospital40 enrolled1 locationNCT07227727