GERD Clinical Trials

40 recruitingLast updated: May 13, 2026

There are 40 actively recruiting gerd clinical trials across 24 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1. Top locations include Hyderabad, Telangana, India, Milwaukee, Wisconsin, United States, Bern, Switzerland. Updated daily from ClinicalTrials.gov.


GERD Trials at a Glance

40 actively recruiting trials for gerd are listed on ClinicalTrialsFinder across 6 cities in 24 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in Hyderabad, Milwaukee, and Bern. Lead sponsors running gerd studies include Asian Institute of Gastroenterology, India, Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology, and Hualien Tzu Chi General Hospital.

Browse gerd trials by phase

Treatments under study

About GERD Clinical Trials

Looking for clinical trials for GERD? There are currently 23 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new GERD trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about GERD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 40 trials

Recruiting
Not Applicable

GERD Infant Feeding Therapeutics Trial (GIFT Trial)

GERD in Infants
Nationwide Children's Hospital369 enrolled1 locationNCT06114836
Recruiting
Phase 2

Transoral Incisional Fundoplication (TIF) for Patients Suffering From Gastroesophageal Reflux Disease in an Asian Population

GERDFundoplication
Chinese University of Hong Kong20 enrolled1 locationNCT07556289
Recruiting
Not Applicable

Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEM

GERD
Asian Institute of Gastroenterology, India300 enrolled1 locationNCT06955520
Recruiting
Not Applicable

Diaphragmatic Training on GERD

GERDDiaphragmatic Training
Changhua Christian Hospital42 enrolled1 locationNCT07544433
Recruiting
Not Applicable

Safety and Effectiveness of eGERD Device to Reduce Gastroesophageal Reflux Disease (GERD) Symptoms

GERD (Gastroesophageal Reflux Disease)
Gerd Care Medical Ltd84 enrolled4 locationsNCT06613438
Recruiting

Esophageal Cancer Risk Registry

Esophageal CancerEsophageal DiseasesEsophageal Achalasia+2 more
University of Pittsburgh7,000 enrolled1 locationNCT00260585
Recruiting
Not Applicable

Performance and Safety of Afluxin® in Patients With Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease (GERD)
Devintec Sagl208 enrolled7 locationsNCT06984484
Recruiting

PRospective Registry of Esophageal Motility

achalasiaeosinophilic esophagitisEsophageal Diseases+2 more
IRCCS San Raffaele10,000 enrolled1 locationNCT07506746
Recruiting
Not Applicable

Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare

GERD (Gastroesophageal Reflux Disease)
Institute of Gastroenterology and Hepatology, Vietnam380 enrolled1 locationNCT07125521
Recruiting
Not Applicable

Compassionate Use of Domperidone for Refractory Gastroparesis

GastroparesisGastroesophageal RefluxGERD
Jose Cocjin20 enrolled1 locationNCT04699591
Recruiting
Phase 2Phase 3

Alginate vs Sucralfate for GERD Symptomatic Relief

GERD
CMH Lahore Medical College and Institute of Dentistry140 enrolled1 locationNCT07310927
Recruiting
Not Applicable

A Randomized, Three-Arm Study Comparing Vonaprazan 10 mg, Vonaprazan 20 mg, and Esomeprazole 40 mg for the Healing of LA Grade B or Higher Reflux Esophagitis at 8 Weeks

GERD
Asian Institute of Gastroenterology, India414 enrolled1 locationNCT06953986
Recruiting
Phase 1

Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.

Gallstone DiseaseIrritable Bowel SyndromeGERD+2 more
Valenta Pharm JSC36 enrolled1 locationNCT07421011
Recruiting
Not Applicable

Mechanisms Preventing Pharyngeal Reflux

GERD
Medical College of Wisconsin300 enrolled1 locationNCT05696184
Recruiting
Phase 2

A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old

Gastroesophageal Reflux Disease (GERD)
Takeda70 enrolled33 locationsNCT02616302
Recruiting
Phase 4

Heartburn, Gastroesophageal Reflux Disease

GERD
Incheon St.Mary's Hospital160 enrolled10 locationsNCT07268820
Recruiting
Not Applicable

GERD in Children With Cystic Fibrosis

GERD in ChildrenCystic Fibrosis in Children
Duke University20 enrolled1 locationNCT06617013
Recruiting
Not Applicable

TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease

GERD (Gastroesophageal Reflux Disease)Hernia, Hiatal
Beijing Friendship Hospital143 enrolled2 locationsNCT07252115
Recruiting

Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:

eosinophilic esophagitisGERD
Medical College of Wisconsin50 enrolled1 locationNCT07227506
Recruiting
Not Applicable

Mesh Vs Pledgets for Repair of Paraesophageal Hernia

Paraesophageal HerniaGERD
David Krpata164 enrolled1 locationNCT05974722