Phase 1 Epithelial Ovarian Cancer Clinical Trials
20 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 20 trials
Recruiting
Phase 1
CT-95 in Advanced Cancers Associated With Mesothelin Expression
Colorectal, CancerMesothelin-Expressing TumorsEpithelial Ovarian Cancer+8 more
Context Therapeutics Inc.70 enrolled9 locationsNCT06756035
Recruiting
Phase 1Phase 2
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Triple-Negative Breast CancerEndometrial CancerPrimary Peritoneal Carcinoma+12 more
Genmab884 enrolled66 locationsNCT05579366
Recruiting
Phase 1Phase 2
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16) pt2
Primary Peritoneal CarcinomaFallopian Tube CarcinomaEpithelial Ovarian Cancer+1 more
Beijing Biotech36 enrolled1 locationNCT07617753
Recruiting
Phase 1
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Ovarian CancerRecurrentOvary Neoplasm+1 more
UNC Lineberger Comprehensive Cancer Center27 enrolled1 locationNCT06305299
Recruiting
Phase 1Phase 2
Dual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian Cancer
Epithelial Ovarian CancerEpithelial Ovarian Cancer, Fallopian Tube or Peritoneum
Beijing Biotech42 enrolled1 locationNCT07589543
Recruiting
Phase 1
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
Solid TumorFallopian Tube CancerEpithelial Ovarian Cancer+1 more
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc172 enrolled24 locationsNCT04516447
Recruiting
Phase 1Phase 2
[18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
Colorectal, CancerGastric CancerPancreatic Ductal Adenocarcinoma+2 more
Blue Earth Diagnostics71 enrolled1 locationNCT07432633
Recruiting
Phase 1
Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy for Recurrent Epithelial Ovarian Cancer
Ovarian CancerRecurrent Epithelial Ovarian Cancer Which Includes Epithelial Ovarian, Fallopian Tube and/or Primary Peritoneal Cancer
PhotonPharma, Inc.8 enrolled1 locationNCT06366490
Recruiting
Phase 1Phase 2
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Breast CancerColorectal, CancerGastric Cancer+10 more
858 Therapeutics, Inc.120 enrolled14 locationsNCT06395519
Recruiting
Phase 1Phase 2
Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
Ovarian CancerPancreatic AdenocarcinomaEpithelial Ovarian Cancer
Case Comprehensive Cancer Center22 enrolled1 locationNCT06412510
Recruiting
Phase 1Phase 2
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)
Primary Peritoneal CarcinomaFallopian Tube CarcinomaEpithelial Ovarian Cancer+1 more
Beijing Biotech36 enrolled1 locationNCT07480954
Recruiting
Phase 1
A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers
Primary Peritoneal CarcinomaFallopian Tube CancerEpithelial Ovarian Cancer
Regeneron Pharmaceuticals90 enrolled5 locationsNCT06469281
Recruiting
Phase 1Phase 2
Study of AVZO-021 in Patients With Advanced Solid Tumors
Endometrial CancerAdvanced Solid TumorTNBC - Triple-Negative Breast Cancer+6 more
Avenzo Therapeutics, Inc.430 enrolled13 locationsNCT05867251
Recruiting
Phase 1Phase 2
NEOadjuvant Dendritic Cell Vaccination for Ovarian Cancer
Ovarian CarcinomaEpithelial Ovarian Cancer
Radboud University Medical Center10 enrolled1 locationNCT05773859
Recruiting
Phase 1
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Colorectal, CancerSquamous Cell Carcinoma of Head and NeckHead and Neck Squamous Cell Carcinoma+8 more
Bicara Therapeutics292 enrolled20 locationsNCT04429542
Recruiting
Phase 1Phase 2
T-regulatory Cell Depletion with E7777 Combined with Pembrolizumab in Recurrent or Metastatic Solid Tumors
Epithelial Ovarian Cancer
Alexander B Olawaiye, MD70 enrolled1 locationNCT05200559
Recruiting
Phase 1
A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers
Triple-Negative Breast CancerEndometrioid Ovarian CancerEpithelial Ovarian Cancer+2 more
Light Chain Bioscience - Novimmune SA70 enrolled7 locationsNCT05403554
Recruiting
Phase 1
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
Triple-Negative Breast CancerColorectal, CancerGastric Cancer+6 more
BioEclipse Therapeutics60 enrolled3 locationsNCT04282044
Recruiting
Phase 1
PET Imaging of Solid Tumors by a Novel Tracer, 68Ga-FAPI
Stomach NeoplasmsPancreatic NeoplasmsEpithelial Ovarian Cancer+1 more
Karolinska University Hospital410 enrolled1 locationNCT05172310
Completed
Phase 1
ANZ 1103 Study of Olaparib Clinical Effect in Patients with Breast Cancer or Ovarian Cancer
Metastatic BRCA-associated breast cancerHigh grade serous epithelial ovarian cancer
Breast Cancer Trials32 enrolled1 locationACTRN12613000924752