Phase 2 Epithelial Ovarian Cancer Clinical Trials

19 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 119 of 19 trials

Recruiting
Phase 2

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Primary Peritoneal CancerFallopian Tube CancerNeoadjuvant+1 more
AbbVie140 enrolled66 locationsNCT06890338
Recruiting
Phase 1Phase 2

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Triple-Negative Breast CancerEndometrial CancerPrimary Peritoneal Carcinoma+12 more
Genmab884 enrolled66 locationsNCT05579366
Recruiting
Phase 1Phase 2

Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16) pt2

Primary Peritoneal CarcinomaFallopian Tube CarcinomaEpithelial Ovarian Cancer+1 more
Beijing Biotech36 enrolled1 locationNCT07617753
Recruiting
Phase 2

A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Primary Peritoneal CancerFallopian Tube CancersAdvanced High-Grade Epithelial Ovarian Cancer
AbbVie110 enrolled52 locationsNCT06682988
Recruiting
Phase 1Phase 2

Dual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian Cancer

Epithelial Ovarian CancerEpithelial Ovarian Cancer, Fallopian Tube or Peritoneum
Beijing Biotech42 enrolled1 locationNCT07589543
Recruiting
Phase 2

Tinzaparin And Biomarkers After Neoadjuvant Treatment of Ovarian Cancer

Epithelial Ovarian Cancer
University Hospital, Linkoeping40 enrolled8 locationsNCT05284552
Recruiting
Phase 2

A Study of Isoquercetin in People With Ovarian Cancer

Ovarian CancerEpithelial Ovarian CancerSerous Ovarian Tumor
Memorial Sloan Kettering Cancer Center90 enrolled8 locationsNCT07303894
Recruiting
Phase 2

Intensification Treatment of Ovarian Cancer by PIPAC

Peritoneal CarcinomatosisAdvanced epithelial ovarian cancer
Moscow Regional Oncological Dispensary160 enrolled1 locationNCT07514494
Recruiting
Phase 1Phase 2

[18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications

Colorectal, CancerGastric CancerPancreatic Ductal Adenocarcinoma+2 more
Blue Earth Diagnostics71 enrolled1 locationNCT07432633
Recruiting
Phase 1Phase 2

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

Breast CancerColorectal, CancerGastric Cancer+10 more
858 Therapeutics, Inc.120 enrolled14 locationsNCT06395519
Recruiting
Phase 1Phase 2

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

Ovarian CancerPancreatic AdenocarcinomaEpithelial Ovarian Cancer
Case Comprehensive Cancer Center22 enrolled1 locationNCT06412510
Recruiting
Phase 1Phase 2

Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)

Primary Peritoneal CarcinomaFallopian Tube CarcinomaEpithelial Ovarian Cancer+1 more
Beijing Biotech36 enrolled1 locationNCT07480954
Recruiting
Phase 2

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

Endometrioid Ovarian CancerFallopian Tube CancerEpithelial Ovarian Cancer+1 more
TORL Biotherapeutics, LLC230 enrolled66 locationsNCT06690775
Recruiting
Phase 1Phase 2

Study of AVZO-021 in Patients With Advanced Solid Tumors

Endometrial CancerAdvanced Solid TumorTNBC - Triple-Negative Breast Cancer+6 more
Avenzo Therapeutics, Inc.430 enrolled13 locationsNCT05867251
Recruiting
Phase 1Phase 2

NEOadjuvant Dendritic Cell Vaccination for Ovarian Cancer

Ovarian CarcinomaEpithelial Ovarian Cancer
Radboud University Medical Center10 enrolled1 locationNCT05773859
Recruiting
Phase 2

WoO: Window of Opportunity Trial of Olaparib and Durvalumab in Histologically Proven EOC

Epithelial Ovarian Cancer
AGO Research GmbH60 enrolled6 locationsNCT04644289
Recruiting
Phase 1Phase 2

T-regulatory Cell Depletion with E7777 Combined with Pembrolizumab in Recurrent or Metastatic Solid Tumors

Epithelial Ovarian Cancer
Alexander B Olawaiye, MD70 enrolled1 locationNCT05200559
Recruiting
Phase 2Phase 3

Application of MRD Combined With Personalized Vaccine in the Treatment of Postoperative Recurrence Prevention of EOC

Epithelial Ovarian Cancer
Second Affiliated Hospital of Wenzhou Medical University10 enrolled1 locationNCT06341907
Completed
Phase 2

Multi-Center, Phase Ib/IIa Safety and Preliminary Efficacy Study of Phenoxodiol (Intravenous Dosage Form and Oral Dosage Form) as a Chemo-Sensitizing Agent for Cisplatin, Carboplatin and Paclitaxel in Epithelial Ovarian Cancer or Primary Peritoneal Cancer that is Platinum- and/or Taxane-Refractory or Resistant.

Recurrent, late-stage epithelial ovarian cancer or primary peritoneal cancer that is refractory or resistant to taxanes and/or platinums.
Marshall Edwards Pty Ltd100 enrolled1 locationACTRN12605000432617