Phase 2 ESS Clinical Trials
494 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 494 trials
Recruiting
Phase 2
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
Major Depressive Disorder (MDD)
Draig Therapeutics Ltd300 enrolled40 locationsNCT07300969
Recruiting
Phase 2
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
Major Depressive DisorderAnxiety Disorders
National Institute of Mental Health (NIMH)3,500 enrolled1 locationNCT00018057
Recruiting
Phase 1Phase 2
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
Myelodysplastic SyndromesMyelofibrosisAnemia+4 more
Disc Medicine, Inc150 enrolled24 locationsNCT05320198
Recruiting
Phase 2
Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study
Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS)24 enrolled1 locationNCT07511049
Recruiting
Phase 1Phase 2
Personalized Ultrasonic Brain Stimulation for Depression (R61)
Depression - Major Depressive DisorderMajor Depressive EpisodeTreatment-Resistant Major Depressive Disorder
Brian Mickey30 enrolled1 locationNCT06902298
Recruiting
Phase 1Phase 2
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
Progressive Metastatic Castrate Resistant Prostate Cancer
Novartis Pharmaceuticals188 enrolled29 locationsNCT07206056
Recruiting
Phase 2
A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)
Myelodysplastic/Myeloproliferative NeoplasmPolycythemia VeraPrimary Myelofibrosis+5 more
National Cancer Institute (NCI)62 enrolled30 locationsNCT06661915
Recruiting
Phase 1Phase 2
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
Hearing DisordersHearing DisorderHearing+7 more
University of Colorado, Denver344 enrolled1 locationNCT07304024
Recruiting
Phase 2
Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD
Posttraumatic Stress DisorderPosttraumatic Headache
Northwestern University175 enrolled3 locationsNCT06608277
Recruiting
Phase 1Phase 2
Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine
SchizophreniaMajor Depressive DisorderBipolar I Disorder
Mapi Pharma Ltd.24 enrolled6 locationsNCT07185815
Recruiting
Phase 2Phase 3
Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
Alcohol MisuseHomeless
University of Oklahoma600 enrolled1 locationNCT06821295
Recruiting
Phase 2
Mindfulness Engaged Neurostimulation for Depression (MEND II)
DepressionDepressive DisorderDepressive Symptoms+2 more
University of California, San Diego120 enrolled1 locationNCT07512284
Recruiting
Phase 1Phase 2
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 2
Ketamine Alcohol (in Treatment-Resistant Depression)
Magnetic Resonance ImagingAlcoholismMajor Depression
Mark Niciu60 enrolled1 locationNCT02122562
Recruiting
Phase 2
Parenting in 2 Worlds Multisite Trial
Substance UseParentingMental Health Wellness 1+1 more
Arizona State University1,440 enrolled4 locationsNCT06324318
Recruiting
Phase 1Phase 2
Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene
Burkitt LymphomaHigh Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 RearrangementsDouble-Expressor Lymphoma
National Cancer Institute (NCI)50 enrolled4 locationsNCT07069699
Recruiting
Phase 2
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)
Progressive Pulmonary FibrosisIdiopathic Pulmonary Fibrosis (IPF)
Avalyn Pharma Inc.340 enrolled52 locationsNCT06951217
Recruiting
Phase 2
Neutralizing Interleukin (IL)-6
Major Depressive Disorder
Icahn School of Medicine at Mount Sinai60 enrolled1 locationNCT07493317
Recruiting
Phase 2
Lysergic Acid Diethylamide (LSD) in Palliative Care
PainQuality of LifePsychological Distress+7 more
University Hospital, Basel, Switzerland60 enrolled4 locationsNCT05883540
Recruiting
Phase 2
Sleep and Stress Study
StressAnxietySleep Disorder (Disorder)
RDC Clinical Pty Ltd240 enrolled1 locationNCT07315516