Fibrosis Clinical Trials in Houston, Texas

33 recruitingHouston, Texas

Showing 120 of 33 trials

Recruiting
Phase 3

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

Interstitial Lung DiseasesFamilial Pulmonary FibrosisInterstitial Lung Abnormalities
Boehringer Ingelheim80 enrolled56 locationsNCT07201922
Recruiting
Phase 3

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Progressive Pulmonary FibrosisInterstitial Lung Disease
United Therapeutics698 enrolled152 locationsNCT05943535
Recruiting
Phase 2

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

Primary MyelofibrosisMyelofibrosis; Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia Myelofibrosis
GlaxoSmithKline68 enrolled33 locationsNCT06517875
Recruiting
Phase 2

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+4 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Phase 3

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

Cystic Fibrosis
Vertex Pharmaceuticals Incorporated210 enrolled38 locationsNCT05422222
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

Cystic Fibrosis
Vertex Pharmaceuticals Incorporated39 enrolled43 locationsNCT05668741
Recruiting
Phase 2

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

LymphomaMyelofibrosisAML (Acute Myelogenous Leukemia)+8 more
Center for International Blood and Marrow Transplant Research358 enrolled13 locationsNCT06859424
Recruiting
Not Applicable

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

Cystic Fibrosis
University of Washington, the Collaborative Health Studies Coordinating Center430 enrolled33 locationsNCT06654752
Recruiting
Not Applicable

Knee Flexionater to Avoid Motion Restoring Surgery

Total Knee AnthroplastyJoint ContracturesKnee Arthrofibrosis
Ermi LLC150 enrolled1 locationNCT07454356
Recruiting

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
Duke University3,000 enrolled41 locationsNCT01915511
Recruiting
Phase 2

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

MyelofibrosisModerate ThrombocytopeniaMild Thrombocytopenia
Karyopharm Therapeutics Inc58 enrolled70 locationsNCT05980806
Recruiting

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

Blood PressureNeuropathyDiabetes+6 more
Jaeb Center for Health Research200 enrolled18 locationsNCT06837181
Recruiting
Phase 2

Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

LymphedemaFibrosisHead &Amp; Neck Cancer+1 more
M.D. Anderson Cancer Center250 enrolled1 locationNCT06912763
Recruiting
Phase 1Phase 2

Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)

Chronic Myelomonocytic Leukemia (CMML)Myelofibrosis (MF)
M.D. Anderson Cancer Center66 enrolled1 locationNCT07128381
Recruiting

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

Cystic Fibrosis
Nicole Hamblett400 enrolled68 locationsNCT06504589
Recruiting
Phase 2

Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF

Idiopathic Pulmonary Fibrosis
Daewoong Pharmaceutical Co. LTD.102 enrolled30 locationsNCT05389215
Recruiting
Phase 1

Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies

Castrate Resistant Prostate CancerNUT CarcinomaChronic Myelomonocytic Leukemia+1 more
Epigenetix, Inc.75 enrolled6 locationsNCT05488548
Recruiting

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

Cystic Fibrosis
Sonya Heltshe210 enrolled35 locationsNCT04509050
Recruiting
Phase 2

Study of TL-895 in Subjects With Myelofibrosis or Indolent Systemic Mastocytosis

MyelofibrosisIndolent Systemic Mastocytosis
Telios Pharma, Inc.121 enrolled52 locationsNCT04655118
Recruiting
Phase 1Phase 2

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

MyelofibrosisPrimary MyelofibrosisPost-PV MF+1 more
Telios Pharma, Inc.70 enrolled19 locationsNCT05280509