Intensive Care Clinical Trials

219 recruitingLast updated: July 11, 2026

There are 219 actively recruiting intensive care clinical trials across 49 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2. Top locations include Paris, France, Nantes, France, Istanbul, Turkey (Türkiye). Updated daily from ClinicalTrials.gov.


Intensive Care Trials at a Glance

219 actively recruiting trials for intensive care are listed on ClinicalTrialsFinder across 6 cities in 49 countries. The largest study group is Not Applicable with 88 trials, with the heaviest enrollment activity in Paris, Nantes, and Istanbul. Lead sponsors running intensive care studies include Assistance Publique - Hôpitaux de Paris, Nantes University Hospital, and Medical University of Vienna.

Browse intensive care trials by phase

Treatments under study

About Intensive Care Clinical Trials

Looking for clinical trials for Intensive Care? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Intensive Care trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Intensive Care clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 219 trials

Recruiting
Not Applicable

The Effects of Endotracheal Suctioning on Pain and Serum Markers

SepsisAdultPneumonia+12 more
Loma Linda University110 enrolled1 locationNCT06692400
Recruiting
Phase 2

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Coronary Artery Bypass Grafting (CABG)Cardiopulmonary BypassIntensive Care Unit+9 more
GCP-Service International West GmbH550 enrolled10 locationsNCT06279793
Recruiting
Phase 2Phase 3

Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo

Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting

Digital and Plasma Biomarkers in Delirium

Sleep QualityCritical IllnessDelirium in the Intensive Care Unit
Scripps Health100 enrolled2 locationsNCT07694206
Recruiting

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

Premature BirthInfant, Extremely PrematureObstetric Labor, Premature+2 more
The University of Texas Health Science Center, Houston5,000 enrolled59 locationsNCT05685745
Recruiting

Intelligent Lung Support in the Intensive Care Unit

Intensive Care MedicineMechanical Ventilation
Technische Universität Dresden530 enrolled5 locationsNCT06595602
Recruiting
Not Applicable

Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure

Intensive Care Units, NeonatalRespiratory Distress Syndrome, NewbornPulmonary Surfactants
Connecticut Children's Medical Center52 enrolled1 locationNCT06446453
Recruiting
Phase 3

Canadian Critical Care Comparative Effectiveness Platform

NutritionVasopressorIntensive Care Unit ICU+1 more
Université de Sherbrooke5,500 enrolled9 locationsNCT06605144
Recruiting

Muscle Recovery After Critical Illness

ICU acquired weaknessMuscle WeaknessCritical Illness+1 more
Esther Dupont-Versteegden209 enrolled3 locationsNCT05537298
Recruiting

The UK 22 Week Study

Infant, Extremely PrematureIntensive Care, NeonatalExtreme Prematurity - Less Than 28 Weeks+1 more
Imperial College London100 enrolled50 locationsNCT07616778
Recruiting
Not Applicable

Effects of PERMISSive Lung-protective Ventilation on Outcome in Critically Ill Invasively Ventilated Patients

Mechanical VentilationIntensive Care (ICU)
Reinier de Graaf Groep56 enrolled5 locationsNCT07077174
Recruiting
Not Applicable

Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

Anxiety AcuteDelirium in the Intensive Care UnitSleep Quality in Adult ICU Patients+1 more
Milton S. Hershey Medical Center30 enrolled1 locationNCT07649876
Recruiting

Mechanical Insufflation-Exsufflation in Critically Ill Patients

Airway ClearanceCritical IllnessCritical Care+5 more
Medipol University30 enrolled4 locationsNCT07420946
Recruiting
Not Applicable

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Septic ShockSepsis - to Reduce Mortality in the Intensive Care Unit
University Hospital, Clermont-Ferrand750 enrolled28 locationsNCT07179276
Recruiting

Multidimensional Dysfunction in Patients With Post-Intensive Care Syndrome in China

Post Intensive Care Syndrome (PICS)
Hongying Jiang, MD800 enrolled4 locationsNCT07585578
Recruiting
Not Applicable

Preventive Narrative Exposure Intervention for PTSD in ICU Patients After Cardiopulmonary Bypass Cardiac Surgery

Stress Disorders, Post-TraumaticCardiopulmonary BypassIntensive Care Units
First Affiliated Hospital of Fujian Medical University100 enrolled1 locationNCT07632131
Recruiting
Not Applicable

Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)

Critical IllnessPost Intensive Care Syndrome (PICS)Cardiopathy
Fondazione Don Carlo Gnocchi ETS326 enrolled1 locationNCT07599306
Recruiting

Identification of Outcome Relevant Indicators in Routine Data

Anesthesiological Risk ReductionIntensive Care Risk Reduction
Charite University, Berlin, Germany1,000,000 enrolled1 locationNCT04670744
Recruiting

Effectiveness of Diaphragmatic Function and Parasternal Intercostal Muscles Functions as Predictors for Successful Weaning From Mechanical Ventilation

Ventilated Patient in Intensive Care
Ain Shams University77 enrolled1 locationNCT07630662
Recruiting
Phase 2

Adjunctive Fludrocortisone in Septic Shock

SepsisSeptic ShockSepsis and septic shock+2 more
Chinese University of Hong Kong32 enrolled5 locationsNCT07451886