Intensive Care Clinical Trials

205 recruitingLast updated: May 21, 2026

There are 205 actively recruiting intensive care clinical trials across 48 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2. Top locations include Paris, France, Nantes, France, Istanbul, Turkey (Türkiye). Updated daily from ClinicalTrials.gov.


Intensive Care Trials at a Glance

205 actively recruiting trials for intensive care are listed on ClinicalTrialsFinder across 6 cities in 48 countries. The largest study group is Not Applicable with 83 trials, with the heaviest enrollment activity in Paris, Nantes, and Istanbul. Lead sponsors running intensive care studies include Assistance Publique - Hôpitaux de Paris, Nantes University Hospital, and Medical University of Vienna.

Browse intensive care trials by phase

About Intensive Care Clinical Trials

Looking for clinical trials for Intensive Care? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Intensive Care trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Intensive Care clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 205 trials

Recruiting
Not Applicable

Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient

Continuous renal replacement therapyAcute Kidney InjuryIntensive Care Unit
Centre Hospitalier Universitaire de Nīmes80 enrolled1 locationNCT06369064
Recruiting
Not Applicable

Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)

Critical IllnessPost Intensive Care Syndrome (PICS)Cardiopathy
Fondazione Don Carlo Gnocchi Onlus326 enrolled1 locationNCT07599306
Recruiting
Phase 3

Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.

AnalgesiaIntensive Care UnitLidocaine
Centre Hospitalier Universitaire, Amiens70 enrolled1 locationNCT03984656
Recruiting
Not Applicable

Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial

Critical Care NursingIntensive Care (ICU)Central Venous Catheter Related Infections+2 more
University Hospital, Angers2,830 enrolled27 locationsNCT07183592
Recruiting
Not Applicable

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)

TemperatureBlood PressureCardiac Arrest (CA)+9 more
Helsinki University Central Hospital3,500 enrolled52 locationsNCT07579390
Recruiting
Phase 3

RECOMMEND Platform Trial

Intensive Care MedicineCritical IllnessCardiac Arrest (CA)+2 more
Australian and New Zealand Intensive Care Research Centre600 enrolled3 locationsNCT06526533
Recruiting
Not Applicable

Comfort Intervention in PICU Children

Anxiety in childrenSleepFear+2 more
Ankara Yildirim Beyazıt University86 enrolled1 locationNCT07441668
Recruiting
Not Applicable

Virtual Reality for Recovery After Intensive Care (PICS)

Cognitive ImpairmentCritical IllnessCritical Illness Recovery+4 more
University of Minho51 enrolled1 locationNCT07585500
Recruiting
Not Applicable

NeoSHARK: Anatomical Versus Round Facemasks for Breathing Support in Preterm and Term Newborn Infants

Neonatal Intensive care
University College Dublin50 enrolled1 locationNCT07524517
Recruiting

CALLY Index, Frailty and SOFA-2 for Mortality Prediction in Geriatric ICU Patients

FrailtyCritical IllnessIntensive Care Unit ICU
Istanbul University - Cerrahpasa100 enrolled1 locationNCT07579728
Recruiting
Not Applicable

Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients

Intradialytic HypotensionHemodialysis PatientsIntensive Care Unit ICU
Chulalongkorn University46 enrolled1 locationNCT07179705
Recruiting

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Intensive Care MedicineOpioid analgesiaExtracorporeal Membrane Oxygenation (ECMO)+5 more
Guy's and St Thomas' NHS Foundation Trust120 enrolled1 locationNCT07032987
Recruiting

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

extubation failureRespiratory FailureWeaning Invasive Mechanical Ventilation+5 more
Medipol University470 enrolled7 locationsNCT07098611
Recruiting

Surviving the Pediatric Intensive Care Unit (PICU)

Post Intensive Care Syndrome (PICS)
KK Women's and Children's Hospital404 enrolled2 locationsNCT06812130
Recruiting

Post Intensive Care Accelerometery to Study and Support Recovery Outcomes

Post Intensive Care Syndrome (PICS)
University of Edinburgh40 enrolled3 locationsNCT07466446
Recruiting
Not Applicable

Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome

Post Intensive Care Syndrome (PICS)
COEN Matteo150 enrolled2 locationsNCT07254299
Recruiting

Communication Enhancement Among Ventilated Patients in Intensive Care

Critical Care, Intensive Care
University Hospital, Tours60 enrolled3 locationsNCT07251530
Recruiting
Not Applicable

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Septic ShockSepsis - to Reduce Mortality in the Intensive Care Unit
University Hospital, Clermont-Ferrand750 enrolled27 locationsNCT07179276
Recruiting

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

Premature BirthInfant, Extremely PrematureObstetric Labor, Premature+2 more
The University of Texas Health Science Center, Houston5,000 enrolled51 locationsNCT05685745
Recruiting

Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.

extubation failureQuality of Life (QOL)Mortality+5 more
Universita degli Studi di Genova2,400 enrolled1 locationNCT07093125