Intensive Care Clinical Trials

15 recruiting

Frequently Asked Questions

Common questions about Intensive Care clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 135 trials

Recruiting
Not Applicable

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Septic ShockSepsis - to Reduce Mortality in the Intensive Care Unit
University Hospital, Clermont-Ferrand750 enrolled23 locationsNCT07179276
Recruiting

UP STUDY - Decipher Persistent Critical Illness Through in Deep Clinical Phenotyping.

Critical IllnessCritical CareCritical Care, Intensive Care+2 more
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa7,000 enrolled7 locationsNCT07510776
Recruiting
Phase 3

Canadian Critical Care Comparative Effectiveness Platform

NutritionVasopressorIntensive Care Unit ICU+1 more
Université de Sherbrooke5,500 enrolled8 locationsNCT06605144
Recruiting
Not Applicable

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)

Mechanical VentilationCritical IllnessNeuromuscular Electrical Stimulation (NMES)+2 more
Hospital Moinhos de Vento150 enrolled1 locationNCT07188350
Recruiting

Variation in Viscoelastic Properties of Pulmonary Mucus in Patients Undergoing Mechanical Ventilation

Ventilated Patient in Intensive Care
Centre Hospitalier Intercommunal Aix-Pertuis20 enrolled1 locationNCT07490028
Recruiting

Functional Incremental Stepping in Place Test (F-IST) Validation

Intensive Care MedicineAcute Care Medical
Kirby Mayer60 enrolled2 locationsNCT06853236
Recruiting
Not Applicable

Biomarker Signature-Supported Antibiotic Treatment Decisions in ICU

Intensive Care Unit (ICU) Admission
McGill University Health Centre/Research Institute of the McGill University Health Centre1,200 enrolled4 locationsNCT07481773
Recruiting

The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients

Ventilated Patient in Intensive CareFailure of Extubation
Ain Shams University70 enrolled1 locationNCT07467265
Recruiting
Not Applicable

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

AnxietyDepression - Major Depressive DisorderPTSD+4 more
Medical University of South Carolina150 enrolled1 locationNCT07390786
Recruiting
Not Applicable

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

ICUIntensive Care UnitCognitive Rehabilitation+1 more
VA Office of Research and Development160 enrolled2 locationsNCT04353804
Recruiting
Phase 2

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

EmergenciesBurnsIntensive Care
Centre Hospitalier Régional Metz-Thionville15 enrolled1 locationNCT06469970
Recruiting
Phase 4

Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes

CardiovascularRed Blood Cell TransfusionsSex Differences+3 more
Michelle Zeller11,082 enrolled8 locationsNCT06840756
Recruiting

Continuous Connected Patient Care (CCPC), a Pilot Testing a Novel Device for Continuous Vitals Monitoring - Department of Anesthesia at PHC

Surgical Procedure, UnspecifiedIntensive Care Units (ICUs)
Medtronic - MITG50 enrolled1 locationNCT06638073
Recruiting
Not Applicable

Impact of an Alarm Management Protocol on Noise Pollution and Patient Safety in Intensive Care Units

Intensive Care Unit
Centre Hospitalier Universitaire de Saint Etienne514 enrolled1 locationNCT06175091
Recruiting
Not Applicable

COPM-Based Goal Setting Strategies in the PICU

Critical IllnessPediatric Intensive Care Unit
Samsung Medical Center5 enrolled2 locationsNCT07128446
Recruiting

IL-6 and Hemogram-Derived Inflammatory Indices for Mortality Prediction in Postoperative ICU Patients

Postoperative ComplicationsInflammationCritical Illness+1 more
Ezgi Günaydın42 enrolled1 locationNCT07460141
Recruiting

Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness

Muscle WeaknessMetabolomicsCritical Illness+4 more
Technical University of Munich20 enrolled3 locationsNCT03810768
Recruiting
Not Applicable

Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit

Diabetes MellitusSepsisCritically Ill Intensive Care Unit Patients+1 more
University Medical Centre Maribor100 enrolled1 locationNCT07448805
Recruiting
Phase 2

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Coronary Artery Bypass Grafting (CABG)Cardiopulmonary BypassIntensive Care Unit+9 more
GCP-Service International West GmbH550 enrolled10 locationsNCT06279793
Recruiting

Dosage of Early Rehabilitation of ICU Patients

PhysiotherapyCritical IllnessCritical Care, Intensive Care+2 more
Medical University of Vienna6,000 enrolled1 locationNCT06960642