Phase 1 Fracture Clinical Trials

11 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 111 of 11 trials

Recruiting
Phase 1

Impact of Early ADL Participation on Outcomes Post DRF

Distal Radius Fracture
George Washington University64 enrolled1 locationNCT05650996
Recruiting
Phase 1

Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

Tibial Plateau Fractures
University of Chicago38 enrolled1 locationNCT06639503
Recruiting
Phase 1Phase 2

Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II

Bone Fracture
BonusBio Group Ltd40 enrolled6 locationsNCT03024008
Recruiting
Phase 1

Impact of Early ADL Education on Outcomes Post DRF ORIF

Distal Radius Fractures
George Washington University64 enrolled1 locationNCT06251206
Recruiting
Phase 1Phase 2

Pilot Study of the α Prototype NIMBLE System: Feasibility, Safety, and Initial Performance in Non-Invasive Detection of Coronary In-Stent Restenosis

In-stent RestenosisStent FractureStent Complication
Nimble Diagnostics S.L.30 enrolled1 locationNCT06968858
Recruiting
Phase 1

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

Bone FractureFresh Fracture
ZetrOZ, Inc.90 enrolled2 locationsNCT05883241
Recruiting
Phase 1Phase 2

Long-term Safety Trial with NVDX3

Distal Radius FracturesDegenerative Lumbar Spondylolisthesis
Novadip Biosciences15 enrolled1 locationNCT06532253
Completed
Phase 1

A Randomised Control Trail to compare the infection rate of topical use of antibiotic vs conventional management of open fractures.

open fracture
Modilon General Hospital120 enrolled1 locationACTRN12619000782134
Not Yet Recruiting
Phase 1

Continuous Infusion Analgesia in Post Surgical Distal Radial Fractures

Unstable Distal Radial Fracture
Dr Ryan Shulman40 enrolled1 locationACTRN12606000450516
Not Yet Recruiting
Phase 1

Aggressive mobilisation following fragment specific fixation of distal radius fractures

Distal radial fractures
Daniel Goldbloom60 enrolled1 locationACTRN12606000160538
Not Yet Recruiting
Phase 1

A safety study of autologous mesenchymal precursor cells (MPCs) in the management of delayed healing tibial fractures requiring secondary surgical intervention to promote fracture union.

Delayed or non-union tibial fracture
Mesoblast10 enrolled1 locationACTRN12605000051640