Phase 3 Fracture Clinical Trials
25 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 25 trials
Recruiting
Phase 3
Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy
Open tíbia Fracture
University of Maryland, Baltimore312 enrolled33 locationsNCT05615844
Recruiting
Phase 3
The MANTRA Trial (MANdibular TRauma and Antibiotic Use)
Mandible FracturePost-operative Antibiotics
East Lancashire Hospitals NHS Trust2,841 enrolled2 locationsNCT05964140
Recruiting
Phase 3
Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs
Rib Fractures
Assiut University60 enrolled1 locationNCT04928300
Recruiting
Phase 3
Intramedullary Calcium Sulfate Antibiotic Depot
Osteomyelitis TibiaTibial FracturesOpen tíbia Fracture
Wake Forest University Health Sciences497 enrolled10 locationsNCT05766670
Recruiting
Phase 3
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
Wrist FracturesDistal Radius Fractures
University of North Carolina, Chapel Hill100 enrolled1 locationNCT06179004
Recruiting
Phase 3
Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures
Pain ControlDistal Radius Fracture ReductionPediatric Fractures
State University of New York at Buffalo50 enrolled1 locationNCT07120763
Recruiting
Phase 3
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
Postoperative Pain ManagementPostoperative Cognitive DysfunctionHip Fracture+1 more
Romanian Society for Enteral and Parenteral Nutrition120 enrolled1 locationNCT07113483
Recruiting
Phase 3
Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma
AsthmaFractures, BoneAllergy+8 more
Professor Klaus Bønnelykke2,000 enrolled1 locationNCT06560255
Recruiting
Phase 3
VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma
AsthmaFractures, BoneAllergy+8 more
Professor Klaus Bønnelykke2,000 enrolled1 locationNCT06570889
Recruiting
Phase 3
A Comparative Study to Valuating the Efficacy and Safety of QL1206 and Prolia®
Postmenopausal Women With Osteoporosis at High Risk of Fracture
Qilu Pharmaceutical Co., Ltd.278 enrolled1 locationNCT07062978
Recruiting
Phase 3
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial
PainTibial Fractures
Major Extremity Trauma Research Consortium1,000 enrolled14 locationsNCT07006675
Recruiting
Phase 3
Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures
Wound HealFracture of Tibia
Major Extremity Trauma Research Consortium352 enrolled2 locationsNCT06337292
Recruiting
Phase 3
Unipolar Versus Bipolar Interlocking in Humeral Shaft Fractures in Adults
Humeral Shaft Fracture
Centre Hospitalier Universitaire Dijon390 enrolled1 locationNCT05877014
Recruiting
Phase 2Phase 3
Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation
Fracture
Naveen Poonai400 enrolled6 locationsNCT04195256
Completed
Phase 3
Efficacy of perioperative Tranexamic Acid in patients undergoing trochanteric hip fracture surgery: A Randomized Placebo Controlled Trial.
blood losship fracture surgery
Dr.Faaiz Ali Shah184 enrolled1 locationACTRN12620001059954
Not Yet Recruiting
Phase 3
Ketamine versus nitrous oxide plus intranasal fentanyl for paediatric fracture reduction in the emergency department: a prospective randomised comparison trial
Paediatric fractures requiring manipulation / reduction
David Bishop216 enrolled1 locationACTRN12619000555156
Not Yet Recruiting
Phase 3
Better ways of pain management in adults with hip fractures
Cognitive ImpairmentHip Fracture Pain Management
Townsville Hospital122 enrolled3 locationsACTRN12618001884291
Not Yet Recruiting
Phase 3Phase 4
Evaluation of outcomes from correction of vitamin D levels in residential care facility residents
Fracturesthe need of hospitalisationacute illnesses and exacerbation of chronic conditions+1 more
ACT Government Health Directorate250 enrolled1 locationACTRN12611000950965
Completed
Phase 3
Effect of Vitamin D Supplementation on Cardiovascular and Respiratory Disease Event Rates, and the incidence of fractures
Non-vertebral fracturesCancerCardiovascular Disease+1 more
University of Auckland5,110 enrolled1 locationACTRN12611000402943
Recruiting
Phase 3Phase 4
Replenishment of Vitamin D in Hip fractured Patients (REVITAHIP) Trial
Hypovitaminosis DRehabilitationHip Fracture
Northern Sydney Central Coast Area Health Service, Gosford Hospital450 enrolled1 locationACTRN12610000392066