Frailty Syndrome Clinical Trials

18 recruiting

Frailty Syndrome Trials at a Glance

18 actively recruiting trials for frailty syndrome are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Reykjavik, Los Angeles, and Bergen. Lead sponsors running frailty syndrome studies include University of Iceland, Haukeland University Hospital, and Fondation Hôpital Saint-Joseph.

Browse frailty syndrome trials by phase

Treatments under study

About Frailty Syndrome Clinical Trials

Looking for clinical trials for Frailty Syndrome? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Frailty Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Frailty Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 118 of 18 trials

Recruiting
Not Applicable

Multimodal Prehabilitation of Frail Patients Undergoing Elective Knee or Hip Replacement

PrehabilitationFrailty SyndromeArthroplasties, Knee Replacement
University of Iceland50 enrolled1 locationNCT07465159
Recruiting

Modified Essential Frailty Toolset in Older Adults Undergoing Major Elective Surgery

Frailty SyndromeFrailty in Adult SurgeryElective Surgeries+2 more
University of Iceland250 enrolled1 locationNCT07452263
Recruiting

Validity of Frailty Screening Tools as a Measure for Postoperative Outcomes

Frailty SyndromeFrailty in Adult Surgery
University of Iceland350 enrolled1 locationNCT07367828
Recruiting
Not Applicable

Real World Evidence to Assess the Value of a Digital Care Coordination and Monitoring Program for Supporting Caregivers of Adults Discharged From the Emergency Department.

Frailty SyndromeCaregiver Burden for Those Who Care for Adults With Impaired Functional Status
Fondation Hôpital Saint-Joseph100 enrolled1 locationNCT07348081
Recruiting

Physical Performance Assessment in Kidney Transplant Evaluation

Frailty Syndrome
University Hospital, Martin50 enrolled1 locationNCT07338929
Recruiting
Not Applicable

Fun Exercise Intervention for Older Adults to Improve Intrinsic Capacity and Motivation

SarcopeniaFrailty Syndrome
Cardenal Herrera University120 enrolled1 locationNCT07133568
Recruiting
Not Applicable

Prehabilitation in Pancreatic Surgery

Pancreatic CancerFrailty SyndromePerioperative/Postoperative Complications+2 more
IRCCS San Raffaele238 enrolled1 locationNCT06069297
Recruiting

The CohorFES: a Prospective Study of Frailty and Dependence

Frailty Syndrome
Parc de Salut Mar1,500 enrolled1 locationNCT06965972
Recruiting
Phase 2

The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging

Frailty SyndromeFrailtyAging+1 more
Haukeland University Hospital100 enrolled2 locationsNCT06208527
Recruiting
Not Applicable

Optimizing Prevention of Hospital-Acquired Disability Through Multidomain Interventions

Frailty SyndromeAging
University of Milano Bicocca288 enrolled1 locationNCT06611228
Recruiting
Not Applicable

Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies

Frailty SyndromeThoracoabdominal Aortic AneurysmThoracoabdominal; Aortic, Aneurysm, Dissecting+1 more
University of Southern California100 enrolled1 locationNCT04524247
Recruiting

Comparison of Frailty Screening Performance and Predictive Validity of Adverse Health Outcomes in Breast Cancer Patients Using Frailty Screening Tools

Frailty Syndrome
Ju Qiu500 enrolled1 locationNCT06467149
Recruiting
Phase 2

Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls

Frailty SyndromeFrailtyFall+1 more
University of Chile60 enrolled1 locationNCT06465602
Recruiting

Movement and Behaviours Measurement Study

Frailty SyndromeAgingPhysical Function+2 more
University of Castilla-La Mancha90 enrolled1 locationNCT04173715
Recruiting

Comprehensive Geriatric Assessment in Kidney Transplantation

Frailty SyndromeKidney Transplant; ComplicationsDepressive Syndrome
Institute for Clinical and Experimental Medicine1,000 enrolled1 locationNCT06104696
Recruiting
Not Applicable

Structured Program of Exercise for Recipients of Kidney Transplantation

Frailty SyndromeKidney Transplant; ComplicationsPhysical Disability+1 more
University of California, San Francisco136 enrolled1 locationNCT04954690
Recruiting

COVID-19 Outcome Prediction Algorithm

Frailty SyndromeCOVID-19Post Acute Sequelae of COVID-19+2 more
University of California, Los Angeles600 enrolled7 locationsNCT05471011
Recruiting

Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People

Frailty SyndromeFrailtyAging+5 more
The Opole University of Technology1,093 enrolled1 locationNCT04518423