Retinal Detachment Clinical Trials

22 recruitingLast updated: June 18, 2026

There are 22 actively recruiting retinal detachment clinical trials across 10 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1. Top locations include Manchester, United Kingdom, Sohag, Sohag Governorate, Egypt, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Retinal Detachment Trials at a Glance

22 actively recruiting trials for retinal detachment are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Manchester, Sohag, and Boston. Lead sponsors running retinal detachment studies include Massachusetts Eye and Ear Infirmary, Sohag University, and Center for Eye Research Australia.

Browse retinal detachment trials by phase

Treatments under study

About Retinal Detachment Clinical Trials

Looking for clinical trials for Retinal Detachment? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Retinal Detachment trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Retinal Detachment clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Phase 3

Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract Removal

rhegmatogenous retinal detachment
Queen's University, Belfast276 enrolled31 locationsNCT06997874
Recruiting
Not Applicable

Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment

Age related macular degeneration (AMD)Diabetic Retinopathy (DR)Retinal Detachment
Fondazione G.B. Bietti, IRCCS260 enrolled1 locationNCT07500324
Recruiting
Not Applicable

Effect of Silicon Oil on Retinal Electrical Functions Using Multifocal Electroretinogram

rhegmatogenous retinal detachment
Minia University50 enrolled1 locationNCT07609628
Recruiting
Not Applicable

Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment

Retinal Displacement After Retinal Detachment Surgery
Norfolk and Norwich University Hospitals NHS Foundation Trust292 enrolled1 locationNCT07027098
Recruiting
Phase 4

Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment

Retinal Detachment
Center for Eye Research Australia144 enrolled5 locationsNCT06587945
Recruiting

Surgical Procedure Efficiency Evaluation stuDy

vitreous hemorrhageCataractRetinal Detachment+2 more
Alcon Research180 enrolled1 locationNCT07228091
Recruiting
Not Applicable

1ry Versus 2ry ILM Peeling in RD

Retinal Detachment RhegmatogenousILM Peeling
Sohag University100 enrolled1 locationNCT07346560
Recruiting
Not Applicable

Spring Loaded Syringe for Active Silicon Oil Extraction

Retinal Detachment
Sohag University200 enrolled1 locationNCT07363889
Recruiting
Not Applicable

Acute Retinal Detachment Repair With the iSeelr™ Retinal Detachment Repair System

Rhegmatogenous Retinal Detachment - Macula Off
Photofuse Pty Ltd10 enrolled1 locationNCT06468397
Recruiting
Not Applicable

High Resolution, High-speed Multimodal Ophthalmic Imaging

HypertensionStrokeDiabetes+12 more
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts1,200 enrolled1 locationNCT04129021
Recruiting
Phase 1Phase 2

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

rhegmatogenous retinal detachmentProliferative Vitreoretinopathy
Massachusetts Eye and Ear Infirmary48 enrolled1 locationNCT06033703
Recruiting

Intraoperative OCT Guidance of Intraocular Surgery II

Epiretinal MembraneHealthyStrabismus+7 more
Duke University262 enrolled1 locationNCT03713268
Recruiting
Not Applicable

hAM for Inferior RRD

rhegmatogenous retinal detachment
Eye & ENT Hospital of Fudan University50 enrolled1 locationNCT07081945
Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study

Retinal diseasesEpiretinal MembraneRetinal Detachment+2 more
The Cleveland Clinic3,000 enrolled1 locationNCT02423213
Recruiting
Phase 4

Dropless Pars Plana Vitrectomy Study

rhegmatogenous retinal detachment
Massachusetts Eye and Ear Infirmary168 enrolled1 locationNCT05331664
Recruiting
Phase 3

Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery

Retinal Detachment
Hopital Foch120 enrolled2 locationsNCT06294847
Recruiting

Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment Patients

rhegmatogenous retinal detachment
First Affiliated Hospital of Chongqing Medical University65 enrolled1 locationNCT06826573
Recruiting
Phase 2

Intravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy

Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
Unity Health Toronto50 enrolled2 locationsNCT05523869
Recruiting
Not Applicable

Comparison of Anatomical and Functional Outcomes of Laser Photocoagulation and Cryopexy in Patients with Rhegmatogenous Retinal Detachment Treated with Pneumatic Retinopexy

rhegmatogenous retinal detachment
Clinical Hospital Center, Split40 enrolled1 locationNCT06694259
Recruiting
Phase 2

Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial

rhegmatogenous retinal detachmentProliferative Vitreoretinopathy
Cincinnati Eye Institute, Southwest Ohio860 enrolled1 locationNCT06541574