Phase 2 GBM Clinical Trials
20 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 20 trials
Recruiting
Phase 2
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled4 locationsNCT07326566
Recruiting
Phase 2
DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)
Glioblastoma (GBM)
Diakonos Oncology Corporation180 enrolled16 locationsNCT06805305
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients
Glioblastoma (GBM)
Myosin Therapeutics Inc.36 enrolled3 locationsNCT07185880
Recruiting
Phase 2
Prophylactic Regimen With Intrathecal Thiotepa in SVZ-positive or Meningeal-risk Glioblastoma
Glioblastoma (GBM)
Second Affiliated Hospital, School of Medicine, Zhejiang University38 enrolled1 locationNCT07511725
Recruiting
Phase 2
Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma
GlioblastomaGBM
Alpheus Medical, Inc.103 enrolled8 locationsNCT07225621
Recruiting
Phase 1Phase 2
Early Phase Study of KESONOTIDE™in Participants With Solid Tumours
Breast CancerLung CancersOvarian Cancer+4 more
Filamon LTD80 enrolled3 locationsNCT06926075
Recruiting
Phase 1Phase 2
5G-PEARL: Paxalisib in Malignant Brain Tumours
Glioblastoma Multiforme (GBM)Malignant Primary Gliomas
Institute of Cancer Research, United Kingdom64 enrolled1 locationNCT07391215
Recruiting
Phase 1Phase 2
5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours
Glioblastoma Multiforme (GBM)Malignant Primary GliomasGlioblastoma Multiform (Grade IV Astrocytoma)+1 more
Institute of Cancer Research, United Kingdom182 enrolled3 locationsNCT06630260
Recruiting
Phase 1Phase 2
Clinical Study of Oncolytic Virus in Glioblastoma
Glioblastoma (GBM)
Mianyang Central Hospital20 enrolled1 locationNCT07145047
Recruiting
Phase 2
Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread
Glioblastoma (GBM)
Second Affiliated Hospital, School of Medicine, Zhejiang University38 enrolled1 locationNCT07193654
Recruiting
Phase 2
G-CSF After Chemo-radiation in Patients With Glioblastoma
Glioblastoma (GBM)MGMT-Methylated GlioblastomaNewly Diagnosed Glioblastoma Multiforme
Massachusetts General Hospital60 enrolled1 locationNCT06649851
Recruiting
Phase 2
Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial
Glioblastoma (GBM)
Brigham and Women's Hospital56 enrolled3 locationsNCT06835803
Recruiting
Phase 1Phase 2
Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection
GBMHigh-Grade GliomasBrain Gliomas
Dushu Lake Hospital Affiliated to Soochow University25 enrolled1 locationNCT06018363
Recruiting
Phase 1Phase 2
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
Brain TumorBrain CancerGlioblastoma+4 more
Northwell Health33 enrolled1 locationNCT02861898
Recruiting
Phase 1Phase 2
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM
CancerBrain TumorBrain Cancer+6 more
Northwell Health67 enrolled1 locationNCT03213002
Recruiting
Phase 1Phase 2
Study of LP-184 in Patients With Advanced Solid Tumors
Advanced Solid TumorMetastatic Solid TumorTNBC - Triple-Negative Breast Cancer+4 more
Lantern Pharma Inc.175 enrolled9 locationsNCT05933265
Recruiting
Phase 2
JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM)
Glioblastoma Multiforme (GBM)
JenKem Technology Co., Ltd.25 enrolled1 locationNCT06595186
Recruiting
Phase 2
Evaluate the Efficacy and Safety of ADCV01 As an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients
GBM
Ever Supreme Bio Technology Co., Ltd.24 enrolled3 locationsNCT04115761
Completed
Phase 2
A Randomised Phase II Study of NivolUmab and TeMozolomide vs Temozolomide alone in newly diagnosed Elderly patients with Glioblastoma (NUTMEG)
Glioblastoma (GBM, astrocytoma WHO grade IV)
The University of Sydney102 enrolled18 locationsACTRN12617000267358
Terminated
Phase 2
AMP: Phase I/II study of AMG 102 and panitumumab in recurrent Glioblastoma Multiforme (GBM)
Recurrent Glioblastoma Multiforme (GBM)
University of Sydney42 enrolled1 locationACTRN12610000092099