Gender Clinical Trials

78 recruitingLast updated: June 21, 2026

There are 78 actively recruiting gender clinical trials across 27 countries. Studies span Not Applicable, Phase 3, Phase 4, Phase 2. Top locations include Ghent, East-Flanders, Belgium, Aurora, Colorado, United States, Vienna, State of Vienna, Austria. Updated daily from ClinicalTrials.gov.


Gender Trials at a Glance

78 actively recruiting trials for gender are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 25 trials, with the heaviest enrollment activity in Ghent, Aurora, and Vienna. Lead sponsors running gender studies include University Hospital, Ghent, University of Colorado, Denver, and Medical University of Vienna.

Browse gender trials by phase

Treatments under study

About Gender Clinical Trials

Looking for clinical trials for Gender? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Gender trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Gender clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 78 trials

Recruiting

Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach

Immune SystemGut MicrobiomeTransgender+1 more
Charite University, Berlin, Germany200 enrolled1 locationNCT05334888
Recruiting
Not Applicable

Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women

ObesityHypertensionDiabetes+4 more
Emory University269 enrolled1 locationNCT07111026
Recruiting
Not Applicable

An Effectiveness Trial of the PrEP for WINGS Study

HIV InfectionsAlcohol Use DisorderViolence, Gender-Based
Columbia University307 enrolled1 locationNCT06853314
Recruiting
Not Applicable

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy

MastectomyGender DysphoriaHypertrophic scar
University of California, San Francisco78 enrolled1 locationNCT07147166
Recruiting

Brain Health in Transgender Adults

Gender Dysphoria
University of Wisconsin, Madison72 enrolled1 locationNCT07624747
Recruiting
Not Applicable

Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients

Hormonal Gender-Affirming Therapy
Mayo Clinic44 enrolled1 locationNCT05587751
Recruiting

GLOW: Gender-Affirming Care and Mental Health: A Longitudinal Study On Quality of Life, Work Life, and Healthcare Outcomes

Gender Dysphoria, Adult
Region Skane500 enrolled1 locationNCT07480590
Recruiting

Pain Outcomes Associated With Exogenous Hormone Therapy in Adults

PainGender Minority Individuals
University of Kansas Medical Center200 enrolled1 locationNCT06939257
Recruiting

Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study

Gender IncongruenceTransgender Individuals
University Hospital, Basel, Switzerland600 enrolled2 locationsNCT06774053
Recruiting
Not Applicable

Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services

StuntingEmpowermentAcceptability of Health Care+2 more
McGill University13,500 enrolled3 locationsNCT06362837
Recruiting
Not Applicable

Developing and Testing a Digital Health Tool for INterseCtional Stigma Assessment and Reduction at Multiple Levels and mUltiple DimEnsions (INCLUDE) to Improve HIV Care in ART Centers in Nepal

Mental Health ConditionsHIV Antiretroviral Therapy (ART) AdherenceStigma+5 more
Possible88 enrolled1 locationNCT07370298
Recruiting
Not Applicable

A Standardized Counseling Approach to Preoperative Education in Transmasculine Individuals Receiving Gender-affirming Surgery

HysterectomyGender Affirming Surgery
University of Minnesota250 enrolled1 locationNCT07324967
Recruiting

Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome

Acute Coronary SyndromeGenetic PredispositionGender
IRCCS San Raffaele100 enrolled4 locationsNCT06441942
Recruiting

Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder

Major Depressive Disorder (MDD)Social StigmaResilience,Psychological+2 more
Eskisehir Osmangazi University90 enrolled1 locationNCT07474363
Recruiting
Not Applicable

Neuromuscular Effects of Acute Fatigue in Adolescent Basketball

GenderFatigue RecoveryBasketball+1 more
Biruni University40 enrolled1 locationNCT07467525
Recruiting

State of Hormones Impact Nociceptive Expression

(Gender) IdentityPain
University of Alabama at Birmingham120 enrolled1 locationNCT05787470
Recruiting
Not Applicable

Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents

Obesity, OverweightEating DisordersBody Image Disturbance+1 more
University of Sao Paulo24 enrolled1 locationNCT07466069
Recruiting

The Effect of Gender-affirmative Measures on Breast Perception in Trans Men

TransgenderGender Dysphoria in Adolescents and Adults
Medical University Innsbruck100 enrolled1 locationNCT07252687
Recruiting

Research Participation With Transgender and Gender-Diverse Youth

Transgender Persons
Virginia Commonwealth University250 enrolled1 locationNCT05927350
Recruiting
Not Applicable

What Works - Malawi SASA! Together

Intimate Partner Violence (IPV)Norms, SocialGender Inequitable Behavior
George Washington University4,800 enrolled1 locationNCT06783400