Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach
Sex Hormone-specific Cardiovascular Risks in the Gut Microbiome-host Axis - A Longitudinal Cohort Study.
Charite University, Berlin, Germany
200 participants
Aug 29, 2022
OBSERVATIONAL
Conditions
Summary
The XCVD study investigates the influence of sex hormones on the composition of the gut microbiome and the possible emergence of cardiovascular risk factors. It will follow 200 healthy transgender individuals for five years during their hormone replacement therapy (HRT) and analyze them for the possible emergence of cardiovascular risk factors in relation to changes in the gut microbiome, metabolome, and immunome. We would also like to phenotype cardiovascular disease.
Eligibility
Plain Language Summary
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Locations(1)
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NCT05334888