Phase 3 Genetic Clinical Trials

7 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 17 of 7 trials

Recruiting
Phase 2Phase 3

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled33 locationsNCT07210723
Recruiting
Phase 3

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Beta-ThalassemiaSickle Cell DiseaseHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated26 enrolled6 locationsNCT05477563
Recruiting
Phase 3

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546
Not Yet Recruiting
Phase 3Phase 4

Topical Dutasteride on Male pattern hairloss.

androgenetic alopecia
Eric Song - Reskin Medical20 enrolled1 locationACTRN12626000082303
Recruiting
Phase 3

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

Skin DiseasesEpidermolysis BullosaConnective Tissue Disease+7 more
Chiesi Farmaceutici S.p.A.6 enrolled6 locationsNCT06917690
Recruiting
Phase 3

Effect of GH on the Blastocyst Euploid Rate in AMA Patients

Preimplantation Genetic TestingGrowth HormoneAge, Parental
ShangHai Ji Ai Genetics & IVF Institute400 enrolled1 locationNCT05447208
Terminated
Phase 3

Genetic Risk Information Disclosure study.

Genetic mutations predisposing to breast, ovarian or colorectal cancer and methods of disclosing that information to relatives.
The Cancer Council Victoria40 enrolled1 locationACTRN12607000316404