Phase 1 Glaucoma Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1Phase 2
Topical Infliximab in Eyes With Penetrating Keratoplasty
Glaucoma Following Surgery
Centre hospitalier de l'Université de Montréal (CHUM)50 enrolled1 locationNCT05180994
Recruiting
Phase 1
Topical Insulin for Glaucoma
Glaucoma
Stanford University52 enrolled1 locationNCT05206877
Recruiting
Phase 1Phase 2
Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting
CataractGlaucomaOphthalmological Disorder
Universiti Kebangsaan Malaysia Medical Centre154 enrolled1 locationNCT05694858
Recruiting
Phase 1
Safety of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
GlaucomaOcular Hypertension
EyeD Pharma18 enrolled1 locationNCT07036510
Withdrawn
Phase 1
A Phase 1 Dose Escalation Safety Study of PBI-671 in Subjects with Glaucoma with Advanced Vision Loss
Glaucoma
Perceive Pharma, Inc.13 enrolled1 locationACTRN12624000785505
Completed
Phase 1
A study to evaluate the Safety, Tolerability, and Pharmacokinetics of SBI-100 Ophthalmic Emulsion in Healthy Adult Participants
Glaucoma
Skye Biosciences,Inc.48 enrolled1 locationACTRN12622000971730
Recruiting
Phase 1
Phase I study of a Latanoprost Ocular Implant for treatment of Open Angle Glaucoma or Ocular Hypertension.
Open Angle GlaucomaOcular Hypertension
PolyActiva Pty Ltd6 enrolled1 locationACTRN12621001718831
Completed
Phase 1
A double-blind, placebo-controlled, randomised trial to determine the ocular pharmacokinetics and safety of oral FT011 in patients with glaucoma.
Glaucoma
Occurx Pty Ltd8 enrolled1 locationACTRN12618000033246
Completed
Phase 1
Avastin in the prevention of postoperative scarring after glaucoma filtration surgery.
Glaucoma, uncontrolled intraocular eye pressure, trabeculectomy, postoperative intervention, subconjunctival delievery.
Monash Universtity50 enrolled1 locationACTRN12607000318482
Completed
Phase 1
Comprehension of medicine label instructions - a pilot study in glaucoma patients.
Glaucoma, medication recall, comprehension of medication instructions, compliance to treatment, visual function, severity of disease.
Catherine Rokhahr, Pharmacy, Royal Victorian Eye and Ear Hospital.200 enrolled1 locationACTRN12607000248460
Recruiting
Phase 1
Intravitreous Avastin for diseases of ocular angiogensis
Neovascular Glaucoma
Royal Victorian Eye and Ear Hospital50 enrolledACTRN12607000244404