Phase 3 Glaucoma Clinical Trials

17 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 117 of 17 trials

Recruiting
Phase 2Phase 3

Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension

OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.60 enrolled1 locationNCT07354516
Recruiting
Phase 3

Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Glaucoma
Glaukos Corporation510 enrolled1 locationNCT07495852
Recruiting
Phase 3

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma
AbbVie130 enrolled21 locationsNCT06822738
Recruiting
Phase 2Phase 3

Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Glaucoma
Glaukos Corporation610 enrolled3 locationsNCT07075718
Recruiting
Phase 3

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

Glaucoma, Open-Angle
Glaukos Corporation230 enrolled1 locationNCT06066645
Recruiting
Phase 3

Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular HypertensionPrimary Open Angle Glaucoma (POAG)
Huons Co., Ltd.206 enrolled1 locationNCT07335211
Recruiting
Phase 3

Pilocarpine Use After Kahook Goniotomy

Glaucoma
Montefiore Medical Center142 enrolled2 locationsNCT03933631
Recruiting
Phase 3

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

CataractGlaucomaOcular Hypertension
SpyGlass Pharma, Inc.400 enrolled1 locationNCT07218796
Recruiting
Phase 3

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)

CataractGlaucomaOcular Hypertension
SpyGlass Pharma, Inc.400 enrolled1 locationNCT07218783
Recruiting
Phase 3

Clarifying the Optimal Application of SLT Therapy Trial

Glaucoma and Ocular Hypertension
University of Pittsburgh790 enrolled29 locationsNCT04967989
Recruiting
Phase 3

A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China

Open Angle GlaucomaOcular Hypertension
Santen Pharmaceutical Co., Ltd.338 enrolled25 locationsNCT06666855
Recruiting
Phase 3

Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial

Glaucoma, Open-Angle
University College, London496 enrolled10 locationsNCT05405868
Recruiting
Phase 3

Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma

Glaucoma, Open-Angle
Omikron Italia S.r.l.1,000 enrolled1 locationNCT05710198
Recruiting
Phase 3

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

Ocular HypertensionGlaucoma, Open-Angle
Amneal Pharmaceuticals, LLC168 enrolled9 locationsNCT05401357
Recruiting
Phase 3

The Vitamin B3 in Glaucoma Study (VBIGS)

Glaucoma
Centre for Eye Research Australia424 enrolled1 locationACTRN12622000414718
Recruiting
Phase 3Phase 4

A biomarker for fast progressors in glaucoma?

Glaucoma
Prof Leung Kai Shun Christopher168 enrolled1 locationACTRN12618000826246
Not Yet Recruiting
Phase 3Phase 4

The Avastin in Trabeculectomy Study

Glaucoma
A/Prof John Landers100 enrolled2 locationsACTRN12614000375651