Glioblastoma Multiforme, Adult Clinical Trials

14 recruiting

Frequently Asked Questions

Common questions about Glioblastoma Multiforme, Adult clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Phase 3

Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma

GlioblastomaNeoplastic DiseaseGlioblastoma (GBM)+3 more
Telix Pharmaceuticals (Innovations) Pty Limited50 enrolled4 locationsNCT07100730
Recruiting
Phase 2

Simultaneous Integrated Boost FDOPA Positron Emission Tomography (PET) Guided in Patients With Partially- or Non-operated Glioblastoma

Glioblastoma Multiforme, Adult
Centre Paul Strauss75 enrolled3 locationsNCT05653622
Recruiting
Phase 2

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Brain CancerGlioblastomaGlioblastoma Multiforme+4 more
Baptist Health South Florida190 enrolled1 locationNCT06991101
Recruiting
Phase 2

hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM)

Glioblastoma MultiformeGlioblastoma Multiforme, AdultSupratentorial Glioblastoma+1 more
Leland Metheny16 enrolled1 locationNCT05052957
Recruiting

Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study

Glioblastoma, AdultGlioblastoma Multiforme, AdultGlioblastoma or Gliosarcoma
Sied Kebir128 enrolled2 locationsNCT06954636
Recruiting
Not Applicable

UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-3 (UNITED-3)

Glioblastoma Multiforme, Adult
Sunnybrook Health Sciences Centre70 enrolled1 locationNCT05720078
Recruiting
Phase 2

UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly

Glioblastoma Multiforme, AdultGlioblastoma, IDH-mutant
Sunnybrook Health Sciences Centre55 enrolled1 locationNCT05565521
Recruiting
Phase 3

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NeoplasmsBrain TumorGlioblastoma+5 more
NaviFUS Corporation32 enrolled2 locationsNCT06496971
Recruiting
Not Applicable

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Brain CancerGlioblastomaGBM+4 more
Northwell Health32 enrolled1 locationNCT05954858
Recruiting
Phase 3

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Brain CancerGlioblastomaGBM+4 more
Northwell Health432 enrolled1 locationNCT05271240
Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+5 more
Jasper Gerritsen464 enrolled8 locationsNCT06283927
Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

Brain NeoplasmsGlioblastomaGlioblastoma, IDH-wildtype+9 more
Jasper Gerritsen784 enrolled8 locationsNCT06118723
Recruiting

The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)

GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+1 more
Jasper Gerritsen1,015 enrolled8 locationsNCT06146738
Recruiting

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+2 more
Jasper Gerritsen564 enrolled8 locationsNCT06146725