Glioma Clinical Trials in Boston, Massachusetts
25 recruitingBoston, Massachusetts
Showing 1–20 of 25 trials
Recruiting
Phase 2
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Pancreatic Neuroendocrine TumorVon Hippel-Lindau DiseasePheochromocytoma/Paraganglioma+2 more
Merck Sharp & Dohme LLC322 enrolled84 locationsNCT04924075
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
MelanomaThyroid CancerGlioma
Pfizer124 enrolled77 locationsNCT05538130
Recruiting
Phase 2
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+7 more
Nationwide Children's Hospital120 enrolled21 locationsNCT05843253
Recruiting
Phase 2
PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
High Grade GliomaDiffuse Intrinsic Pontine GliomaRecurrent Medulloblastoma
Nationwide Children's Hospital120 enrolled12 locationsNCT05096481
Recruiting
Targeted Pediatric High-Grade Glioma Therapy
Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+6 more
Nationwide Children's Hospital350 enrolled21 locationsNCT05839379
Recruiting
Phase 1
rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Ann & Robert H Lurie Children's Hospital of Chicago36 enrolled3 locationsNCT04943848
Recruiting
Early Phase 1
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital15 enrolled21 locationsNCT04655404
Recruiting
Early Phase 1
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Phase 1
CUE-102 in Recurrent Glioblastoma
GlioblastomaGlioma, MalignantRecurrent Glioblastoma
David Reardon, MD18 enrolled2 locationsNCT06917885
Recruiting
Phase 3
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
GliomaAstrocytoma, IDH-Mutant, Grade 2Astrocytoma, Grade IV+5 more
Nuvation Bio Inc.365 enrolled45 locationsNCT05303519
Recruiting
Phase 3
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc.400 enrolled138 locationsNCT05566795
Recruiting
Phase 1Phase 2
CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Lymphoma+7 more
Children's Oncology Group63 enrolled34 locationsNCT04870944
Recruiting
Phase 1
CARv3-TEAM-E T Cells in Glioblastoma
GlioblastomaMalignant GliomaRecurrent Glioblastoma+1 more
Marcela V. Maus, M.D.,Ph.D.21 enrolled1 locationNCT05660369
Recruiting
Not Applicable
NeuroPathways Intervention for Brain Tumor Patients
GliomaMalignant Brain TumorCoping Skills
Massachusetts General Hospital50 enrolled1 locationNCT05976490
Recruiting
Phase 2
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Recurrent Diffuse Intrinsic Pontine GliomaDiffuse Intrinsic Pontine GliomaWHO Grade III Glioma+3 more
University of California, San Francisco360 enrolled32 locationsNCT05009992
Recruiting
Early Phase 1
Implantable Microdevice In Primary Brain Tumors
GlioblastomaAstrocytomaGrade II Glioma+5 more
Oliver Jonas12 enrolled1 locationNCT04135807
Recruiting
Not Applicable
ASCENT Intervention for Brain Tumor Patients
Distress, EmotionalGliomaMalignant Brain Tumor+1 more
Massachusetts General Hospital100 enrolled1 locationNCT06099743
Recruiting
Phase 1
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults
GlioblastomaMalignant GliomaRecurrent Glioblastoma+3 more
Sabine Mueller, MD, PhD20 enrolled20 locationsNCT04323046
Recruiting
Phase 2
Study of Olutasidenib and Temozolomide in HGG
Metastatic Brain TumorIDH1 MutationAstrocytoma, Grade IV+16 more
Rigel Pharmaceuticals60 enrolled18 locationsNCT06161974
Recruiting
Not Applicable
MCT for the Harvard/UCSF ROBIN Center
NeuroblastomaGlioma, Childhood Brainstem
Brigham and Women's Hospital47 enrolled2 locationsNCT06000787