GvHD Clinical Trials

36 recruitingLast updated: June 17, 2026

There are 36 actively recruiting gvhd clinical trials across 10 countries. Studies span Phase 2, Phase 3, Early Phase 1, Not Applicable, Phase 1. Top locations include Duarte, California, United States, New York, New York, United States, Atlanta, Georgia, United States. Updated daily from ClinicalTrials.gov.


GvHD Trials at a Glance

36 actively recruiting trials for gvhd are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Phase 2 with 19 trials, with the heaviest enrollment activity in Duarte, New York, and Atlanta. Lead sponsors running gvhd studies include Royal Brisbane and Women's Hospital, Incyte Corporation, and Daihong Liu.

Browse gvhd trials by phase

Treatments under study

About GvHD Clinical Trials

Looking for clinical trials for GvHD? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new GvHD trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about GvHD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 36 trials

Recruiting
Phase 3

Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD

cGVHD
Xuzhou Medical University20 enrolled1 locationNCT06244628
Recruiting
Phase 2

A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

GvHDUndefinedGraft-Versus-Host Disease
Memorial Sloan Kettering Cancer Center44 enrolled9 locationsNCT05675930
Recruiting
Phase 3

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Graft-Versus-Host-Disease (GVHD)
Incyte Corporation572 enrolled30 locationsNCT06615050
Recruiting
Phase 2

Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease

Chronic Graft Versus Host DiseasecGVHD
University of Miami49 enrolled1 locationNCT06663722
Recruiting
Phase 2

Low-Dose ATG/PTCy Plus Ivarmacitinib for aGVHD Prevention in Haplo-PBSCT From Parous Female Donors

Graft-Versus-Host-Disease (GVHD)Bone Marrow Transplantation
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine82 enrolled1 locationNCT07570745
Recruiting

Evaluation of Patients With Immune Function Abnormalities

Chronic Granulomatous Disease (CGD)X-Linked Severe Combined Immune Deficiency (XSCID)Leukocyte Adhesion Deficiency 1 (LAD)+1 more
National Institute of Allergy and Infectious Diseases (NIAID)3,500 enrolled1 locationNCT00128973
Recruiting

CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease

GVHD,Acute
Henry Ford Health System100 enrolled1 locationNCT05718791
Recruiting
Phase 3

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor

GvHD
Assistance Publique - Hôpitaux de Paris324 enrolled28 locationsNCT06083129
Recruiting
Phase 1Phase 2

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Early Phase 1

A Clinical Study Evaluating the Safety and Efficacy of GT729 Universal Cell Injection in the Treatment of Refractory or Relapsed Chronic Graft-versus-host Disease (cGVHD)

cGVHD
Grit Biotechnology36 enrolled1 locationNCT07253259
Recruiting
Phase 2

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Chronic Graft-Versus-Host Disease (cGVHD)
H. Lee Moffitt Cancer Center and Research Institute120 enrolled5 locationsNCT06660355
Recruiting
Not Applicable

Diagnostic Refinement and Educational Approaches in Managing Bone Marrow Transplantation

GvHDBone Marrow Transplant Complications
Scripps Health60 enrolled1 locationNCT06590285
Recruiting
Phase 2

Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

Graft-Versus-Host-Disease (GVHD)allogeneic stem cell transplantationHematologic Malignancies
Milton S. Hershey Medical Center41 enrolled1 locationNCT06926595
Recruiting
Phase 2

Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease)

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu54 enrolled1 locationNCT07509749
Recruiting
Not Applicable

A Trial to Evaluate the Safety and Preliminary Efficacy of iMesenchymal Stromal Cells(iMSC) in Subjects With SR-aGVHD

Steroid-refractory Acute Graft-versus-host Disease(SR-aGVHD)
Anhui Provincial Hospital12 enrolled1 locationNCT06321198
Recruiting

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

cGVHD
Incyte Corporation1,500 enrolled32 locationsNCT05919511
Recruiting

Improvement of Women's Health After Allogeneic Stem Cell Transplantation

GVHD, Chronic
Ciusss de L'Est de l'Île de Montréal100 enrolled1 locationNCT06279676
Recruiting
Phase 2

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Acute Myelogenous LeukemiaMyelodysplastic SyndromesAcute Lymphocytic Leukemia+1 more
Case Comprehensive Cancer Center36 enrolled1 locationNCT06904482
Recruiting

2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD

oGVHDDry-Eye Disease
University of Maryland, Baltimore150 enrolled1 locationNCT04946721
Recruiting
Phase 2

Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu168 enrolled1 locationNCT07340723