GvHD Clinical Trials

1 recruiting

GvHD Trials at a Glance

23 actively recruiting trials for gvhd are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Phase 2 with 11 trials, with the heaviest enrollment activity in Duarte, Los Angeles, and Atlanta. Lead sponsors running gvhd studies include Royal Brisbane and Women's Hospital, Case Comprehensive Cancer Center, and Byung-Sik Cho.

Browse gvhd trials by phase

Treatments under study

About GvHD Clinical Trials

Looking for clinical trials for GvHD? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new GvHD trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about GvHD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting

Evaluation of Patients With Immune Function Abnormalities

Chronic Granulomatous Disease (CGD)X-Linked Severe Combined Immune Deficiency (XSCID)Leukocyte Adhesion Deficiency 1 (LAD)+1 more
National Institute of Allergy and Infectious Diseases (NIAID)3,500 enrolled1 locationNCT00128973
Recruiting

CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease

GVHD,Acute
Henry Ford Health System100 enrolled1 locationNCT05718791
Recruiting
Phase 1Phase 2

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Early Phase 1

A Clinical Study Evaluating the Safety and Efficacy of GT729 Universal Cell Injection in the Treatment of Refractory or Relapsed Chronic Graft-versus-host Disease (cGVHD)

cGVHD
Grit Biotechnology36 enrolled1 locationNCT07253259
Recruiting
Not Applicable

A Trial to Evaluate the Safety and Preliminary Efficacy of iMesenchymal Stromal Cells(iMSC) in Subjects With SR-aGVHD

Steroid-refractory Acute Graft-versus-host Disease(SR-aGVHD)
Anhui Provincial Hospital12 enrolled1 locationNCT06321198
Recruiting

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

cGVHD
Incyte Corporation1,500 enrolled32 locationsNCT05919511
Recruiting

Improvement of Women's Health After Allogeneic Stem Cell Transplantation

GVHD, Chronic
Ciusss de L'Est de l'Île de Montréal100 enrolled1 locationNCT06279676
Recruiting
Phase 2

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Acute Myelogenous LeukemiaMyelodysplastic SyndromesAcute Lymphocytic Leukemia+1 more
Case Comprehensive Cancer Center36 enrolled1 locationNCT06904482
Recruiting
Phase 2

Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu168 enrolled1 locationNCT07340723
Recruiting

Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).

GVHD, ChronicGVHD - Graft-Versus-Host Disease
Medical University of Gdansk200 enrolled1 locationNCT07314892
Recruiting
Phase 2

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC48 enrolled26 locationsNCT06619561
Recruiting
Phase 2

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease

Steroid Refractory GVHD
ReAlta Life Sciences, Inc.66 enrolled11 locationsNCT06343792
Recruiting

The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients

Ocular GVHD
Indiana University30 enrolled1 locationNCT04700657
Recruiting
Phase 2

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

Acute LeukemiaGVHD,AcuteMyelodysplastic Syndromes+1 more
University of Alabama at Birmingham29 enrolled1 locationNCT06315309
Recruiting
Early Phase 1

Treatment of Refractory cGVHD by Donor-derived Treg Cell Injection Combined With Recombinant Human Interleukin-2

cGVHD
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine18 enrolled1 locationNCT06920199
Recruiting
Phase 2

Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease

Chronic Graft Versus Host DiseasecGVHD
University of Miami49 enrolled1 locationNCT06663722
Recruiting
Phase 1

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Hematologic MalignancyGvHDGVHD,Acute+8 more
Tr1X, Inc.36 enrolled5 locationsNCT06462365
Recruiting
Phase 2

Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moderate or Higher Severity

NeoplasmsGVHD - Graft-Versus-Host DiseaseHaematopoietic Stem Cell Transplantation
Byung-Sik Cho88 enrolled1 locationNCT06756061
Recruiting

Cell Free DNA Profiling As a Tool to Monitor Clinically-Relevant Events in Allogeneic Hematopoietic Stem Cell Transplantation

GVHD - Graft-Versus-Host DiseaseInfections After HSCTTransplant Associated Microangiopathy TAM+2 more
University of Turin, Italy30 enrolled2 locationsNCT06715046
Recruiting
Phase 3

Use of Tocilizumab (TCZ) to prevent acute graft versus host disease (GVHD) randomized trial

Acute graft versus host disease (GVHD) post HLA-matched allogeneic haematopoietic progenitor cell transplantation (HPCT)
Royal Brisbane and Women's Hospital110 enrolled1 locationACTRN12614000266662