Phase 2 GvHD Clinical Trials
11 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–11 of 11 trials
Recruiting
Phase 1Phase 2
Prebiotic Galacto-oligosaccharide and Acute GVHD
Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Phase 2
Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood
Acute Myelogenous LeukemiaMyelodysplastic SyndromesAcute Lymphocytic Leukemia+1 more
Case Comprehensive Cancer Center36 enrolled1 locationNCT06904482
Recruiting
Phase 2
Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )
GVHD,AcuteStem Cell Transplant Complications
Daihong Liu168 enrolled1 locationNCT07340723
Recruiting
Phase 2
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC48 enrolled26 locationsNCT06619561
Recruiting
Phase 2
Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease
Steroid Refractory GVHD
ReAlta Life Sciences, Inc.66 enrolled11 locationsNCT06343792
Recruiting
Phase 2
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Acute LeukemiaGVHD,AcuteMyelodysplastic Syndromes+1 more
University of Alabama at Birmingham29 enrolled1 locationNCT06315309
Recruiting
Phase 2
Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease
Chronic Graft Versus Host DiseasecGVHD
University of Miami49 enrolled1 locationNCT06663722
Recruiting
Phase 2
Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moderate or Higher Severity
NeoplasmsGVHD - Graft-Versus-Host DiseaseHaematopoietic Stem Cell Transplantation
Byung-Sik Cho88 enrolled1 locationNCT06756061
Recruiting
Phase 2
Use of Tocilizumab (TCZ) to prevent acute graft versus host disease (GVHD)
Acute graft versus host disease (GVHD) post HLA-matched allogeneic haematopoietic progenitor cell transplantation (HPCT)
Royal Brisbane and Women's Hospital18 enrolled1 locationACTRN12614000212651
Recruiting
Phase 2
Use of Tocilizumab (TCZ) to prevent acute graft versus host disease (GVHD)
Acute graft versus host disease (GVHD) post HLA-matched allogeneic haematopoietic progenitor cell transplantation (HPCT)
Royal Brisbane and Women's Hospital48 enrolled1 locationACTRN12612000726853
Recruiting
Phase 2
A pilot study of combining rituximab and low-dose (1.0Gy) total nodal irradiation in treatment of extensive chronic graft-versus-host disease
Chronic graft-versus-host disease (GVHD)
Simon He and Andrew Grigg20 enrolled1 locationACTRN12607000628448