Phase 2 GvHD Clinical Trials
19 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–19 of 19 trials
Recruiting
Phase 2
A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant
GvHDUndefinedGraft-Versus-Host Disease
Memorial Sloan Kettering Cancer Center44 enrolled9 locationsNCT05675930
Recruiting
Phase 2
Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease
Chronic Graft Versus Host DiseasecGVHD
University of Miami49 enrolled1 locationNCT06663722
Recruiting
Phase 2
Low-Dose ATG/PTCy Plus Ivarmacitinib for aGVHD Prevention in Haplo-PBSCT From Parous Female Donors
Graft-Versus-Host-Disease (GVHD)Bone Marrow Transplantation
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine82 enrolled1 locationNCT07570745
Recruiting
Phase 1Phase 2
Prebiotic Galacto-oligosaccharide and Acute GVHD
Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Phase 2
Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy
Chronic Graft-Versus-Host Disease (cGVHD)
H. Lee Moffitt Cancer Center and Research Institute120 enrolled5 locationsNCT06660355
Recruiting
Phase 2
Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention
Graft-Versus-Host-Disease (GVHD)allogeneic stem cell transplantationHematologic Malignancies
Milton S. Hershey Medical Center41 enrolled1 locationNCT06926595
Recruiting
Phase 2
Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease)
GVHD,AcuteStem Cell Transplant Complications
Daihong Liu54 enrolled1 locationNCT07509749
Recruiting
Phase 2
Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood
Acute Myelogenous LeukemiaMyelodysplastic SyndromesAcute Lymphocytic Leukemia+1 more
Case Comprehensive Cancer Center36 enrolled1 locationNCT06904482
Recruiting
Phase 2
Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )
GVHD,AcuteStem Cell Transplant Complications
Daihong Liu168 enrolled1 locationNCT07340723
Recruiting
Phase 2
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC48 enrolled26 locationsNCT06619561
Recruiting
Phase 2
Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation
Graft-Versus-Host-Disease (GVHD)Hematological Malignancies
University of Nebraska126 enrolled1 locationNCT06799195
Recruiting
Phase 2
BPC2001 for the Prevention of Acute Graft-Versus-Host Disease Following Haploidentical Stem Cell Transplantation
Graft-Versus-Host DiseaseaGVHDcGVHD+1 more
BioPhoenix Co., Ltd.50 enrolled1 locationNCT07246031
Recruiting
Phase 2
Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease
Steroid Refractory GVHD
ReAlta Life Sciences, Inc.66 enrolled11 locationsNCT06343792
Recruiting
Phase 2
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Acute LeukemiaGVHD,AcuteMyelodysplastic Syndromes+1 more
University of Alabama at Birmingham29 enrolled1 locationNCT06315309
Recruiting
Phase 2
Dapagliflozin in Allo-HCT for aGVHD
Graft-Versus-Host-Disease (GVHD)
The First Affiliated Hospital of Soochow University72 enrolled1 locationNCT06626737
Recruiting
Phase 2
Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moderate or Higher Severity
NeoplasmsGVHD - Graft-Versus-Host DiseaseHaematopoietic Stem Cell Transplantation
Byung-Sik Cho88 enrolled1 locationNCT06756061
Recruiting
Phase 2
Use of Tocilizumab (TCZ) to prevent acute graft versus host disease (GVHD)
Acute graft versus host disease (GVHD) post HLA-matched allogeneic haematopoietic progenitor cell transplantation (HPCT)
Royal Brisbane and Women's Hospital18 enrolled1 locationACTRN12614000212651
Recruiting
Phase 2
Use of Tocilizumab (TCZ) to prevent acute graft versus host disease (GVHD)
Acute graft versus host disease (GVHD) post HLA-matched allogeneic haematopoietic progenitor cell transplantation (HPCT)
Royal Brisbane and Women's Hospital48 enrolled1 locationACTRN12612000726853
Recruiting
Phase 2
A pilot study of combining rituximab and low-dose (1.0Gy) total nodal irradiation in treatment of extensive chronic graft-versus-host disease
Chronic graft-versus-host disease (GVHD)
Simon He and Andrew Grigg20 enrolled1 locationACTRN12607000628448