RecruitingPhase 2NCT06289049

Heavy Strength Training in Head and Neck Cancer Survivors

Feasibility and Preliminary Efficacy of Heavy Lifting Strength Training Versus Usual Care in Head and Neck Cancer Survivors: A Randomized Controlled Trial

Sponsor

University of Alberta

Enrollment

60 participants

Start Date

Feb 17, 2025

Study Type

INTERVENTIONAL

Conditions

Head and Neck Carcinoma Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Head and Neck Neoplasms

Summary

Despite improvements in treatments, head and neck cancer survivors (HNCS) still endure acute and chronic side effects such as loss of muscular strength, limitations in physical functioning, fatigue, and swallowing difficulties that impact quality of life (QoL) and limit return to work. Light-to-moderate intensity strength training (LMST) has been shown to improve some side effects. Heavy lifting strength training (HLST) may further improve outcomes in some populations, however, only one small pilot study has focused on HNCS. The LIFTING 2 trial will be the first to examine the feasibility and effects of a HLST program versus no exercise in HNCS.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a heavy strength training program can safely improve strength and muscle function in survivors of head and neck cancer who have finished treatment. **You may be eligible if...** - You are 18 or older and have had any type or stage of head and neck cancer - You finished cancer treatment at least 1 year ago - You have enough shoulder mobility to participate in strength training exercises - Your oncologist and a certified exercise professional have cleared you for exercise - You can communicate in English **You may NOT be eligible if...** - You have already been doing regular strength training (at least 2 days per week) in the past month - You are currently enrolled in another exercise or drug trial - You have unmanaged medical conditions or substance use issues Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERExperimental

Three primary exercises will be included in the exercise sessions for participants randomized to this group: barbell back squat, bench press, and dead lift The weight will be progressively increased overtime based on participants' perceived exertion and repetitions in reserve. Number of repetitions performed for each exercise will begin at 10 repetitions in weeks 1-2, with gradual progression to lifting heavier loads of 3-5 sets of 1-5 repetitions between weeks 6-12.

Locations(1)

University of Alberta

Edmonton, Alberta, Canada

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NCT06289049

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