Head and Neck Neoplasms Clinical Trials

28 recruiting

Head and Neck Neoplasms Trials at a Glance

28 actively recruiting trials for head and neck neoplasms are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Manchester, Milwaukee, and Bethesda. Lead sponsors running head and neck neoplasms studies include University of Chicago, Brown University, and Associacao de Investigacao de Cuidados de Suporte em Oncologia.

Browse head and neck neoplasms trials by phase

Treatments under study

About Head and Neck Neoplasms Clinical Trials

Looking for clinical trials for Head and Neck Neoplasms? There are currently 28 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Head and Neck Neoplasms trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Head and Neck Neoplasms clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 28 trials

Recruiting

Biospecimen Procurement for Head and Neck Disorders

Head and Neck NeoplasmsLaryngeal DiseaseHearing Disorder+2 more
National Cancer Institute (NCI)1,000 enrolled9 locationsNCT03429036
Recruiting
Not Applicable

Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients

Head and Neck CarcinomaHead and Neck CancerHead and Neck Neoplasms
University of California, San Francisco120 enrolled1 locationNCT07556367
Recruiting
Not Applicable

Preventive Physical Activity Intervention in Head and Neck Cancer

Head and Neck NeoplasmsPhysical Inactivity
Sahlgrenska University Hospital80 enrolled1 locationNCT05432297
Recruiting

The EMINENCE Study - PET/MR Imaging of Head Neck Cancer

Head and Neck Neoplasms
Norwegian University of Science and Technology390 enrolled2 locationsNCT04612075
Recruiting

Molecular and Genomic Profiling of Head and Neck Tumors

Head and Neck Neoplasms
Montefiore Medical Center1,000 enrolled1 locationNCT00200486
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting
Phase 2

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

Head and Neck CarcinomaHead and Neck CancerHead and Neck Squamous Cell Carcinoma+1 more
Memorial Sloan Kettering Cancer Center12 enrolled6 locationsNCT05544136
Recruiting
Phase 2

Heavy Strength Training in Head and Neck Cancer Survivors

Head and Neck CarcinomaHead and Neck CancerHead and Neck Squamous Cell Carcinoma+1 more
University of Alberta60 enrolled1 locationNCT06289049
Recruiting
Not Applicable

Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study

Head and Neck CancerHead and Neck NeoplasmsXerostomia
Universidad de Granada60 enrolled1 locationNCT05106608
Recruiting
Phase 3

Head and Neck Cancer Study Project in the Geriatric Population

Head and Neck Neoplasms
Brown University20 enrolled1 locationNCT06998069
Recruiting
Phase 2

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

Head and Neck CancerHead and Neck Squamous Cell CarcinomaHead and Neck Neoplasms+2 more
University of Chicago30 enrolled1 locationNCT05420948
Recruiting
Phase 1

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

Head and Neck NeoplasmsNeoplasm MetastasisCarcinoma, Squamous Cell+3 more
University of Chicago36 enrolled1 locationNCT06912087
Recruiting

NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

Head and Neck NeoplasmsHearing LossHearing Disorders+1 more
National Institute on Deafness and Other Communication Disorders (NIDCD)1,000 enrolled1 locationNCT06303180
Recruiting
Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Breast NeoplasmsColorectal NeoplasmsHead and Neck Neoplasms+1 more
Rutgers, The State University of New Jersey100 enrolled12 locationsNCT07158164
Recruiting
Phase 1Phase 2

HTL0039732 in Participants With Advanced Solid Tumours

SarcomaUrinary Bladder NeoplasmsUterine Cervical Neoplasms+11 more
Cancer Research UK150 enrolled5 locationsNCT05944237
Recruiting
Not Applicable

The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

Head and Neck CancerSurvivorshipHead and Neck Neoplasms+1 more
Medical University of South Carolina352 enrolled1 locationNCT05811936
Recruiting
Phase 2

Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors

MelanomaHead and Neck NeoplasmsMSI-H Cancer
University Medical Center Groningen97 enrolled1 locationNCT05483400
Recruiting
Phase 3

Upfront Surgery Vs Induction Chemotherapy Followed By Surgery In Oral Cancers:

Head and Neck NeoplasmsOral Cancer
All India Institute of Medical Sciences, Jodhpur346 enrolled7 locationsNCT06737822
Recruiting
Not Applicable

EMST in Patients Undergoing CRT for HNCA

Head and Neck NeoplasmsDeglutition Disorders
University of Wisconsin, Milwaukee30 enrolled2 locationsNCT03916809
Recruiting

Arabic PRO Measures for Head and Neck Cancer Radiotherapy.

Head and Neck CancerHead and Neck Squamous Cell CarcinomaHead and Neck Neoplasms+5 more
King Saud University125 enrolled1 locationNCT06662929