Early Phase 1 Healt Clinical Trials
39 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 39 trials
Recruiting
Early Phase 1
A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity
First in Man Study to Evaluate Initial SafetyOverweight and Obese AdultsHealthy Participants Study
Zealand Pharma88 enrolled1 locationNCT07721597
Recruiting
Early Phase 1
FLOAT for Healthcare PTSS
Posttraumatic stress symptomsPTSDPost-traumatic Stress Symptoms+4 more
Laureate Institute for Brain Research, Inc.15 enrolled1 locationNCT07710417
Recruiting
Early Phase 1
Safety and Pharmacokinetics Study of Multiple Ascending Doses of VV913 Capsules
Healthy Volunteers
Vigonvita Life Sciences24 enrolled1 locationNCT07507838
Recruiting
Early Phase 1
Repeated CBD Administration and Cannabis Outcomes
CannabisAbuse LiabilityExperimental Pain in Healthy Human Participants
Hannah Harris23 enrolled1 locationNCT07434895
Recruiting
Early Phase 1
Positron Emission Tomography (PET) Contrast Agent Kinetics and Safety: [18F]-Fluoromannitol
Healthy
St. Jude Children's Research Hospital10 enrolled1 locationNCT07110519
Recruiting
Early Phase 1
Psilocybin Administration With 5-HT1a Blockade
Psychedelic Effects in Healthy Volunteers
Johns Hopkins University18 enrolled1 locationNCT07565493
Recruiting
Early Phase 1
Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis
Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)100 enrolled1 locationNCT06615986
Recruiting
Early Phase 1
Evaluation of [¹⁸F]MODAG-009 PET Imaging in Synucleinopathies
Parkinson DiseaseHealthy AdultMultiple System Atrophy (MSA)
MODAG GmbH13 enrolled1 locationNCT07640555
Recruiting
Early Phase 1
Evaluation of the Pharmacokinetics, Biodistribution and Radiation Dosimetry of [18F]MODAG-009 Positron Emission Tomography (PET) Radiotracers in Adult Healthy Volunteers
Healthy Adult
MODAG GmbH6 enrolled1 locationNCT07617688
Recruiting
Early Phase 1
An Experimental Medicine Multicenter Trial to Evaluate the Safety and Immunogenicity of Experimental Versus Authorized SARS-CoV-2 Vaccine Candidates as a Booster Dose in Healthy Participants Previously Vaccinated With Authorized mRNA SARS-CoV-2 Vaccines.
Healthy Adults
ANRS, Emerging Infectious Diseases48 enrolled3 locationsNCT07605520
Recruiting
Early Phase 1
Radiocaine Safety Study
Healthy Subjects
Lutroo Imaging LLC6 enrolled1 locationNCT07081217
Recruiting
Early Phase 1
The Role of NaV1.8 in Human Pain Models
PainHealthy Volunteer StudyAcute Pain
Medical University of Vienna66 enrolled1 locationNCT07511400
Recruiting
Early Phase 1
The Dosimetry, Safety and Diagnostic Efficacy of ⁶⁸Ga-FC516 in Healthy Subjects and Patients With Prostate Cancer
Prostate CancerHealthy Adult
FindCure Biosciences (ZhongShan) Co., Ltd.10 enrolled1 locationNCT07468708
Recruiting
Early Phase 1
Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1
healthy adult participants
Yale University32 enrolled1 locationNCT07457736
Recruiting
Early Phase 1
Impact of Exogenous Ketones on Breathing in Healthy Volunteers
Healthy Volunteer
Johns Hopkins University20 enrolled1 locationNCT07220122
Recruiting
Early Phase 1
Single-tracer Multiparametric PET Imaging
Cardiovascular DiseaseHealthy Subjects
University of California, Davis60 enrolled1 locationNCT06014515
Recruiting
Early Phase 1
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Neurological injuryStrokeHealthy Volunteers+3 more
Northwell Health64 enrolled1 locationNCT04755699
Recruiting
Early Phase 1
SV2A Density Cannabis Use Disorder
HealthyCannabis Use Disorder
Yale University51 enrolled1 locationNCT05472818
Recruiting
Early Phase 1
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
Heat StrainHealthy Volunteer StudyKidney Dysfunction
Beth Israel Deaconess Medical Center28 enrolled2 locationsNCT06983730
Recruiting
Early Phase 1
Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
Healthy
Mayo Clinic56 enrolled1 locationNCT05538247