Phase 1 Healthy Volunteers Clinical Trials
136 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 136 trials
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics of GenSci161 in Healthy Adult Participants
Healthy Volunteers
Changchun GeneScience Pharmaceutical Co., Ltd.44 enrolled1 locationNCT07476586
Recruiting
Phase 1Phase 2
Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause
Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 1
The Primary Purpose of This Study is to Determine if Biotin, Vitamin B7 is an Effective Way to Label Platelets in Survival and Recovery Studies.
Healthy Volunteers
Bloodworks12 enrolled1 locationNCT07513532
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 1Phase 2
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1
A Dose-Escalation Study of RO7875913 in Healthy Participants
Healthy Volunteers
Genentech, Inc.40 enrolled1 locationNCT07342114
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases
Healthy ParticipantsHealthy VolunteersAutoimmune Diseases+1 more
BeiGene211 enrolled13 locationsNCT06342713
Recruiting
Phase 1
Phase I Study of HXN6005 in Adult Healthy Participants
Healthy Volunteers (HV)
Helixon Biotechnology (Suzhou) Co., Ltd32 enrolled1 locationNCT07449741
Recruiting
Phase 1
Safety of Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteer
Healthy VolunteersNon Diabetic Hyperglycemia
Chulalongkorn University48 enrolled1 locationNCT07532135
Recruiting
Phase 1
A Study to Evaluate the Effect of Food on the Bioavailability of AJ201, and Safety, Tolerability, and Pharmacokinetics of AJ201 in Japanese and White Healthy Male Participants
Food Effect in Healthy VolunteersHealthy Male Adults
AnnJi Pharmaceutical Co., Ltd.26 enrolled1 locationNCT07549919
Recruiting
Phase 1
A Study to Evaluate Single and Multiple Doses of SEP-479 in Healthy Adult Participants
Healthy Volunteers
Septerna, Inc.150 enrolled1 locationNCT07433179
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 1
A Study to Evaluate ALN-4285 in Adult Healthy Volunteers
Healthy Volunteers
Alnylam Pharmaceuticals76 enrolled1 locationNCT07295717
Recruiting
Phase 1Phase 2
To studyJUV-161 Administered to Healthy Volunteers Undergoing Unilateral Lower Limb Immobilization (ULLI)
Healthy Volunteers
Juvena Therapeutics36 enrolled2 locationsNCT07397468
Recruiting
Phase 1
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants
Healthy Volunteers
Hoffmann-La Roche128 enrolled1 locationNCT07271693
Recruiting
Phase 1
A Study of ORN252 in Healthy Participants
Healthy Volunteers - Male and Female
Orna Therapeutics, Inc.20 enrolled1 locationNCT07439796
Recruiting
Phase 1Phase 2
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Healthy Volunteers
Regeneron Pharmaceuticals172 enrolled6 locationsNCT05648214
Recruiting
Phase 1
A Study to Evaluate ALN-4915 in Adult Healthy Volunteers
Healthy Volunteers
Alnylam Pharmaceuticals44 enrolled1 locationNCT07535606
Recruiting
Phase 1
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
Healthy VolunteersOverweight or Obesity
Hoffmann-La Roche30 enrolled2 locationsNCT07499050
Recruiting
Phase 1
A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together
Healthy Volunteers
Otsuka Pharmaceutical Development & Commercialization, Inc.48 enrolled1 locationNCT07446400