Phase 2 Healthy Volunteers Clinical Trials
18 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–18 of 18 trials
Recruiting
Phase 2
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 1Phase 2
Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause
Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 1Phase 2
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 1Phase 2
To studyJUV-161 Administered to Healthy Volunteers Undergoing Unilateral Lower Limb Immobilization (ULLI)
Healthy Volunteers
Juvena Therapeutics36 enrolled2 locationsNCT07397468
Recruiting
Phase 1Phase 2
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Healthy Volunteers
Regeneron Pharmaceuticals172 enrolled6 locationsNCT05648214
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 2
Ultralow Dose PET Imaging of SSTR2 Radiotracer Uptake
Healthy VolunteersHealthy (Controls)Neuroendocrine (NE) Tumors
Akiva Mintz200 enrolled1 locationNCT07284589
Recruiting
Phase 2
Neurobiology of Suicide
DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1Phase 2
Dose Escalation Trial of CD40.Pan.CoV Vaccine, Adjuvanted or Not, as a Booster in Adult Healthy Volunteers
Healthy Volunteers
ANRS, Emerging Infectious Diseases48 enrolled7 locationsNCT07113106
Recruiting
Phase 1Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Healthy VolunteersAnemia, Sickle Cell
Bristol-Myers Squibb184 enrolled19 locationsNCT06481306
Recruiting
Phase 1Phase 2
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled1 locationNCT07231679
Recruiting
Phase 1Phase 2
Classroom Break, Cognition, and Fitness in Elementary School Children
Healthy Volunteers
Purdue University352 enrolled1 locationNCT06258941
Recruiting
Phase 2Phase 3
Effects of Rifaximin on Gut Microbiota and Emotion
StressHealthy VolunteersFear
Universitaire Ziekenhuizen KU Leuven60 enrolled1 locationNCT05587036
Recruiting
Phase 2
Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body
Heart FailureCardiometabolic SyndromeCardiovascular Diseases+2 more
National Heart Centre Singapore200 enrolled1 locationNCT06645691
Recruiting
Phase 2
To Evaluate Dose and Safety of NanoEcho Particle-1 Using NanoEcho Imaging Device Examinations of Rectal Lymph Nodes in Healthy Volunteers and Rectal Cancer Patients.
Healthy VolunteersRectal Cancer Patients
NanoEcho AB12 enrolled1 locationNCT06693375
Completed
Phase 2
A pilot trial of vitamin D for the reduction of chronic disease and mortality in older adults.
This trial is using healthy volunteers from the electoral roll. The overall aim of this study is to determine the feasibility and inform the design of a large-scale randomised, placebo-controlled chemoprevention trial of vitamin D3 (cholecalciferol) for the reduction of total mortality.
Queensland Institute of Medical Research660 enrolled1 locationACTRN12609001063202