Early Phase 1 Heart Clinical Trials

10 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 110 of 10 trials

Recruiting
Early Phase 1

Oral Carnitine in Heart Failure Patients

Heart FailureCarnitine Deficiency
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's20 enrolled1 locationNCT07201714
Recruiting
Early Phase 1

SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

Heart Failure With Preserved Ejection FractionType2 Diabetes
The University of Texas Health Science Center at San Antonio30 enrolled1 locationNCT05057806
Recruiting
Early Phase 1

Ketones, SGLT2, HFrEF

Heart Failure With Reduced Ejection FractionType2diabetes
The University of Texas Health Science Center at San Antonio71 enrolled1 locationNCT06229678
Recruiting
Early Phase 1

Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

Type 2 DiabetesHeart Failure, Reduced Ejection Fraction
The University of Texas Health Science Center at San Antonio10 enrolled1 locationNCT06108076
Recruiting
Early Phase 1

Diffusion MRI in Heart Failure

Heart FailureMyocardial InfarctionLeft Ventricular Hypertrophy
Massachusetts General Hospital160 enrolled1 locationNCT02973633
Recruiting
Early Phase 1

Thiamine Intervention and Coronary Artery Bypass Grafting

Coronary Heart DiseaseCoronary Artery Bypass Grafting
University of California, Los Angeles52 enrolled1 locationNCT06326996
Recruiting
Early Phase 1

Cardiac Power Output in Cardiogenic Shock Patients

Heart FailureCardiogenic Shock
University of Chicago5 enrolled1 locationNCT05700617
Recruiting
Early Phase 1

Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children

Respiratory DiseasesCongenital Heart Defects
Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan110 enrolled1 locationNCT06267859
Recruiting
Early Phase 1

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

Univentricular Heart
Boston Children's Hospital10 enrolled1 locationNCT05744934
Not Yet Recruiting
Early Phase 1

Everolimus for the prevention of calcineurin-inhibitor-induced left ventricular hypertrophy in heart transplantation

Left ventricular hypertrophy in heart transplantation
St. Vincent`s Hospital40 enrolled4 locationsACTRN12614000387628