Helicobacter Pylori Clinical Trials

59 recruitingLast updated: June 18, 2026

There are 59 actively recruiting helicobacter pylori clinical trials across 19 countries. Studies span Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1. Top locations include Shanghai, Shanghai Municipality, China, Taipei, Taiwan, Jinan, Shandong, China. Updated daily from ClinicalTrials.gov.


Helicobacter Pylori Trials at a Glance

59 actively recruiting trials for helicobacter pylori are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Phase 4 with 18 trials, with the heaviest enrollment activity in Shanghai, Taipei, and Jinan. Lead sponsors running helicobacter pylori studies include National Taiwan University Hospital, Shanghai Jiao Tong University School of Medicine, and Tanta University.

Browse helicobacter pylori trials by phase

Treatments under study

About Helicobacter Pylori Clinical Trials

Looking for clinical trials for Helicobacter Pylori? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Helicobacter Pylori trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Helicobacter Pylori clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 59 trials

Recruiting

Effect of PPIs on Stool DNA Test for H. Pylori

Helicobacter Pylori Infection
Shanghai Jiao Tong University School of Medicine25 enrolled1 locationNCT07516262
Recruiting
Not Applicable

Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori

Helicobacter Pylori
National Institute of Allergy and Infectious Diseases (NIAID)25 enrolled1 locationNCT06871579
Recruiting
Phase 3

Effect of Bismuth Add-on to Dual Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori Infections
National Taiwan University Hospital990 enrolled1 locationNCT07576959
Recruiting
Not Applicable

Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication

Helicobacter Pylori Infection
Peking University First Hospital70 enrolled1 locationNCT07439445
Recruiting
Not Applicable

Tegoprazan-containing Sequential for H. Pylori

Helicobacter Pylori Infection
Seoul National University Bundang Hospital400 enrolled1 locationNCT06382493
Recruiting
Phase 4

Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication

Peptic ulcer diseaseHelicobacter Pylori InfectionDyspepsia+2 more
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh80 enrolled2 locationsNCT07537634
Recruiting
Not Applicable

Efficacy and Safety of 14-Day Vonoprazan-Based Dual Therapy Versus Quadruple Therapy for Helicobacter Pylori Eradication: A Multicentre, Non-Inferiority Randomized Controlled Trial

Helicobacter Pylori Infections
Yanqing Li372 enrolled2 locationsNCT07179159
Recruiting
Phase 4

Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection

Helicobacter Pylori Infection
National Taiwan University Hospital450 enrolled1 locationNCT05332444
Recruiting
Phase 4

Eradication of Helicobacter Pylori Improves Metabolic Syndrome Through Modulation of Gut Microbiota.

Metabolic SyndromeHelicobacter Pylori Infections
Nanjing First Hospital, Nanjing Medical University120 enrolled1 locationNCT07306988
Recruiting
Phase 4

7-Day Vonoprazan, High-Dose Amoxicillin, and Bismuth Therapy

Helicobacter Pylori
The First Affiliated Hospital with Nanjing Medical University316 enrolled1 locationNCT07232095
Recruiting

Registry for the Management of Helicobacter Pylori Infection in Shandong Province

Helicobacter Pylori Infections
Yueyue Li10,000 enrolled2 locationsNCT07335406
Recruiting

Prevalence of Helicobacter Pylori Infection and Gastric Cancer in the West Indies

Stomach NeoplasmsGastric NeoplasmsHelicobacter Pylori
University Hospital Center of Martinique112 enrolled1 locationNCT04949737
Recruiting

Changes Associated With H. Pylori and Gastric Carcinogenesis

Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Weill Medical College of Cornell University120 enrolled1 locationNCT02164409
Recruiting

Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy

Helicobacter Pylori InfectionsIntestinal MetaplasiaBarett's Esophagus
Sigmund Freud PrivatUniversitat1,000 enrolled1 locationNCT07346521
Recruiting
Not Applicable

H. Pylori Eradication With Argon Plasma During Endoscopy

Helicobacter Pylori InfectionHelicobacter PyloriH.Pylori Infection+2 more
Christopher C. Thompson, MD, MSc20 enrolled1 locationNCT06529159
Recruiting

Prospective Gastric Cancer Screening Using Helicobacter Pylori High-Risk Single Nucleotide Polymorphism Detection

Gastric AdenocarcinomaHelicobacter Pylori
Fudan University15,000 enrolled1 locationNCT06943781
Recruiting
Phase 2

Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection

Helicobacter Pylori InfectionsHelicobacter InfectionHelicobacter Pylori Gastrointestinal Tract Infection+1 more
Tanta University66 enrolled1 locationNCT07293910
Recruiting
Not Applicable

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy and Bismuth Quadruple Therapy

Helicobacter Pylori Infection
Kaohsiung Medical University552 enrolled1 locationNCT07358130
Recruiting
Not Applicable

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication

Helicobacter Pylori Eradication
Kaohsiung Medical University390 enrolled1 locationNCT06349486
Recruiting

P-CABs-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori Infection
Yueyue Li1,730 enrolled1 locationNCT07285096