Phase 2 Hematologic Malignancy Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 1Phase 2

Clinical Study of the Safety and Efficacy of Allogeneic TCR-enhanced Vδ2 T Cell in Patients With Malignant Tumors.

Solid TumorHematologic Malignancy
Chinese PLA General Hospital24 enrolled1 locationNCT07570563
Recruiting
Phase 2

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

Non-Hodgkin LymphomaHematologic MalignancyMantle Cell Lymphoma
M.D. Anderson Cancer Center30 enrolled1 locationNCT05529069
Recruiting
Phase 2

GM-CSF With Post-Transplant Cyclophosphamide

Transplant-Related Hematologic Malignancy
Northside Hospital, Inc.38 enrolled1 locationNCT04237623
Recruiting
Phase 1Phase 2

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

Relapsed Hematologic MalignancyRefractory Hematologic MalignancyRelapsed Primary Central Nervous System Lymphoma+1 more
Curis, Inc.152 enrolled45 locationsNCT03328078
Recruiting
Phase 2

A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant

Hematologic MalignancyGraft vs Host DiseaseGraft-Versus-Host Disease
Memorial Sloan Kettering Cancer Center46 enrolled8 locationsNCT07006506
Recruiting
Phase 2

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+21 more
Masonic Cancer Center, University of Minnesota70 enrolled1 locationNCT05735717
Recruiting
Phase 2

Study of Posaconazole Prophylaxis in Patients Receiving Hematopoietic Stem Cell Allograft (Allo-HSC) at High Risk of Invasive Fungal Infection (IFI)

Hematologic Malignancy
Nantes University Hospital30 enrolled1 locationNCT06541067
Recruiting
Phase 2

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation

Hematologic MalignancyGraft-Versus-Host Disease
Nantes University Hospital82 enrolled3 locationsNCT06252870
Recruiting
Phase 1Phase 2

A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe.

Acute Leukemia, High RiskMyelodysplastic Syndromes, High RiskHematologic Malignancy Requiring an Allogeneic Hematopoietic Stem Cell Transplant Lacking a Donor
Ciusss de L'Est de l'Île de Montréal7 enrolled1 locationNCT07301866
Recruiting
Phase 1Phase 2

Study Evaluating the Safety and the Efficacy of Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution After Umbilical Cord Blood (UCB) Transplantation in Adult Patients With Hematologic Malignancies (HTLP-ONCO)

Hematologic Malignancy
Assistance Publique - Hôpitaux de Paris10 enrolled5 locationsNCT04707300
Recruiting
Phase 2

Cold Versus Room Temperature Storage of Platelets for Bleeding in Hematologic Malignancy - a Pilot Trial

Hematologic Malignancy
Ottawa Hospital Research Institute50 enrolled1 locationNCT05820126
Recruiting
Phase 1Phase 2

CD45RA Depleted DLI After TCRα/β Depleted Haploidentical HCT

Hematologic Malignancy
University Hospital Tuebingen60 enrolled2 locationsNCT05943067
Recruiting
Phase 1Phase 2

CD7-specific CAR-T Cell in the Treatment of CD7-positive Relapsed/Refractory Hematologic Tumors

Hematologic Malignancy
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology80 enrolled1 locationNCT06720324
Recruiting
Phase 1Phase 2

TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies

Acute Myeloid LeukemiaNon-Hodgkin LymphomaHematologic Malignancy+2 more
Shenzhen TargetRx Co., Ltd.30 enrolled1 locationNCT06206174
Recruiting
Phase 2

Azacitidine in Combination With Venetoclax Treatment for MRD Positive Post Allo-HSCT AML/MDS Patients

Hematologic MalignancyStem Cell Transplant Complications
First Affiliated Hospital of Zhejiang University95 enrolled1 locationNCT04809181