Phase 1 Hepatitis B Clinical Trials
42 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 42 trials
Recruiting
Phase 1
hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis
Hepatitis B
Sclnow Biotechnology Co., Ltd.20 enrolled1 locationNCT03826433
Recruiting
Phase 1
A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B Virus (Hbv)
Jiyan Liu9 enrolled1 locationNCT07051187
Recruiting
Phase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
Hepatitis B Virus Infection
GigaGen, Inc.48 enrolled16 locationsNCT07024641
Recruiting
Phase 1
A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B
Chronic Hepatitis B Virus Infection
IntegerBio90 enrolled1 locationNCT07389044
Recruiting
Phase 1
Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 1
SA1211 Injection Phase 1 Study
Chronic Hepatitis B
Suzhou Siran Biotechnology Co.,Ltd.80 enrolled1 locationNCT07275918
Recruiting
Phase 1
TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B
Hepatitis BChronic Hepatitis B
University of Maryland, Baltimore10 enrolled1 locationNCT04843852
Recruiting
Phase 1
A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease
Hepatitis B
GlaxoSmithKline32 enrolled1 locationNCT07168356
Recruiting
Phase 1
A Study of SN2001 Dose, Safety & Immunogenicity in Healthy Adults
Chronic Hepatitis B Infection
Chimivac INC36 enrolled1 locationNCT07059403
Recruiting
Phase 1
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Universitätsklinikum Hamburg-Eppendorf24 enrolled2 locationsNCT05727267
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in subjects with chronic Hepatitis B Infection, including subjects with Chronic Hepatitis D infection
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc50 enrolled3 locationsACTRN12625000281493
Not Yet Recruiting
Phase 1
Safety and Tolerability of CLB-4000 in Subjects with Chronic Hepatitis B: Randomised cohort
Chronic Hepatitis B
ClearB Therapeutics, Inc.8 enrolled1 locationACTRN12625000250437
Not Yet Recruiting
Phase 1
Safety and Tolerability of CLB-4000 in Subjects with Chronic Hepatitis B: non-randomised cohorts
Chronic Hepatitis B
ClearB Therapeutics, Inc.17 enrolled1 locationACTRN12625000204448
Recruiting
Phase 1Phase 2
A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma
Hepatitis B Virus Related Hepatocellular CarcinomaHepatocellular Carcinoma Recurrent
SCG Cell Therapy Pte. Ltd.46 enrolled6 locationsNCT05417932
Not Yet Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc60 enrolled6 locationsACTRN12625000142437
Recruiting
Phase 1
Safety and Antiviral Activity of a Monoclonal Hepatitis B Antibody (The SAMBA Study)
Hepatitis B
Aarhus University Hospital30 enrolled1 locationNCT06668727
Recruiting
Phase 1
A Study of SCG101 TCR-T Cell Therpay in the Treatment of Subjects With Hepatitis B Virus-Related
Hepatocellular CarcinomaHCCHepatitis B Virus Related Hepatocellular Carcinoma
SCG Cell Therapy Pte. Ltd.38 enrolled7 locationsNCT06617000
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in Healthy volunteers
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc.80 enrolled1 locationACTRN12624001003561
Not Yet Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc80 enrolled6 locationsACTRN12624000809538