Phase 1 Hepatitis B Clinical Trials
50 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 50 trials
Recruiting
Phase 1Phase 2
TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Michael Hoelscher81 enrolled6 locationsNCT06513286
Recruiting
Phase 1
Safety and Antiviral Activity of a Monoclonal Hepatitis B Antibody: a Phase 1b, Open-label Trial in Individuals With Chronic Hepatitis D Infection
Hepatitis D, ChronicHepatitis B Chronic Infection
Aarhus University Hospital15 enrolled2 locationsNCT07610772
Recruiting
Phase 1
A Phase I Clinical Study of AHB - 171 in Healthy Participants(HP) and Chronic Hepatitis B (CHB) Participants
Chronic Hepatitis B Infection
Ausper Biopharma Co., Ltd.110 enrolled1 locationNCT07511218
Recruiting
Phase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
Hepatitis B Virus Infection
GigaGen, Inc.48 enrolled17 locationsNCT07024641
Recruiting
Phase 1
hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis
Hepatitis B
Sclnow Biotechnology Co., Ltd.20 enrolled1 locationNCT03826433
Recruiting
Phase 1
A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B Virus (Hbv)
Jiyan Liu9 enrolled1 locationNCT07051187
Recruiting
Phase 1
A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B
Chronic Hepatitis B Virus Infection
IntegerBio90 enrolled1 locationNCT07389044
Recruiting
Phase 1
Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 1
HepB mAb19 in Individuals With Chronic Hepatitis B Infection
Hepatitis BHepatitis B Virus
Rockefeller University37 enrolled2 locationsNCT05856890
Recruiting
Phase 1
Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B
Chronic Hepatitis BHBVChronic Hep B+1 more
Tune Therapeutics, Inc.36 enrolled3 locationsNCT06671093
Recruiting
Phase 1
SA1211 Injection Phase 1 Study
Chronic Hepatitis B
Suzhou Siran Biotechnology Co.,Ltd.80 enrolled1 locationNCT07275918
Recruiting
Phase 1
TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B
Hepatitis BChronic Hepatitis B
University of Maryland, Baltimore10 enrolled1 locationNCT04843852
Recruiting
Phase 1
A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease
Hepatitis B
GlaxoSmithKline32 enrolled1 locationNCT07168356
Recruiting
Phase 1
Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B
Hepatitis B, Chronic
Precision BioSciences, Inc.45 enrolled4 locationsNCT06680232
Recruiting
Phase 1
A Study of SN2001 Dose, Safety & Immunogenicity in Healthy Adults
Chronic Hepatitis B Infection
Chimivac INC36 enrolled1 locationNCT07059403
Recruiting
Phase 1
HBV-Specific TCR-T Cell Therapy Combined With Nucleos(t)Ide Analogues in Chronic Hepatitis B Patients
Chronic Hepatitis B
Changhai Hospital19 enrolled1 locationNCT06885710
Recruiting
Phase 1
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Universitätsklinikum Hamburg-Eppendorf24 enrolled2 locationsNCT05727267
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in subjects with chronic Hepatitis B Infection, including subjects with Chronic Hepatitis D infection
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc50 enrolled3 locationsACTRN12625000281493
Not Yet Recruiting
Phase 1
Safety and Tolerability of CLB-4000 in Subjects with Chronic Hepatitis B: Randomised cohort
Chronic Hepatitis B
ClearB Therapeutics, Inc.8 enrolled1 locationACTRN12625000250437