Hepatitis B Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Hepatitis B clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 25 trials

Recruiting
Phase 1

Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function

Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Not Applicable

Screening for Hepatitis B, Hepatitis C and AIDS Viruses Using Dried Blood Spot

Hepatitis BHepatitis CAIDS
University Hospital, Rouen500 enrolled11 locationsNCT05390424
Recruiting

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Liver CancerNon-Alcoholic Fatty Liver DiseaseNon Alcoholic Steatohepatitis+4 more
Institut National de la Santé Et de la Recherche Médicale, France800 enrolled1 locationNCT04690972
Recruiting

Evaluation of Patients With Liver Disease

Hepatitis BHepatitis CLiver Disease+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)8,050 enrolled1 locationNCT00001971
Recruiting
Phase 2

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 4

National Liver Cancer Screening Trial

Liver CancerCarcinoma, HepatocellularLiver Cirrhosis+1 more
University of Texas Southwestern Medical Center5,500 enrolled18 locationsNCT06084234
Recruiting

The Role and Regulatory Mechanism of Germinal Center Immune Response in Hepatitis B Virus Infection

Hepatitis B Virus Infection
Nanfang Hospital, Southern Medical University280 enrolled1 locationNCT07240350
Recruiting

Abbreviated Magnetic Resonance Imaging vs Ultrasound Surveillance for Liver Cancer dETection in People at High Risk of Developing Liver Cancer

Hepatocellular CarcinomaCirrhosisCirrhosis Due to Hepatitis B+3 more
University of Oxford300 enrolled2 locationsNCT06658782
Recruiting

Liver Disease and Other Systemic Diseases

Hepatocellular CarcinomaHumansTreatment Outcome+7 more
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation15,000 enrolled1 locationNCT04525833
Recruiting
Not Applicable

Gene Discovery in CHB Patients to Identify Unknown Pathways That Lead to B and NK Cell Deregulation

Chronic Hepatitis B Virus
University Hospital, Limoges140 enrolled3 locationsNCT06853886
Recruiting

Observation Study on Reducing the Risk of Liver Cancer Associated With Hepatitis B (Zhiyuan) Project.

Chronic Hepatitis B
The First Affiliated Hospital of Zhengzhou University15,000 enrolled162 locationsNCT07169656
Recruiting

Blood Collection Biorepository for Liver Disease Research

CirrhosisFibrosisHepatitis B+5 more
State University of New York at Buffalo1,000 enrolled1 locationNCT03025074
Recruiting

Real-world Study Evaluating the Long-term Outcomes of Pegylated Interferon α-2b Treatment in the Families With Clusters of HBV Infection and Unfavorable Prognosis - A Prospective, Controlled, Multicenter, Cohort Study

Hepatitis B, Chronic (CHB)Hepatitis BHepatitis B Virus (HBV)
First Affiliated Hospital Xi'an Jiaotong University1,500 enrolled2 locationsNCT07079150
Recruiting

The HOPE Study: Characterizing Patients With Hepatitis B and C

Hepatitis CHepatitis B, Chronic
University of Maryland, Baltimore550 enrolled2 locationsNCT02995252
Recruiting

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

HIV InfectionsHepatitis B
Syneos Health24,258 enrolled1 locationNCT00404989
Recruiting

New HBV Infection Biomarkers: Clinical Characterization and Impact on Management

Chronic Hepatitis B Virus (HBV) Infection
Assistance Publique - Hôpitaux de Paris900 enrolled1 locationNCT06906016
Recruiting

Non-Invasive Model for Fibrosis Regression in HBV Patients

Chronic Hepatitis B Virus (HBV) InfectionLiver Fibrosis
Beijing Friendship Hospital1,100 enrolled1 locationNCT06874127
Recruiting
Phase 1Phase 2

A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma

Hepatitis B Virus Related Hepatocellular CarcinomaHepatocellular Carcinoma Recurrent
SCG Cell Therapy Pte. Ltd.46 enrolled6 locationsNCT05417932
Recruiting
Phase 1

A Study of SCG101 TCR-T Cell Therpay in the Treatment of Subjects With Hepatitis B Virus-Related

Hepatocellular CarcinomaHCCHepatitis B Virus Related Hepatocellular Carcinoma
SCG Cell Therapy Pte. Ltd.38 enrolled7 locationsNCT06617000
Recruiting
Phase 2

Liver Cancer Disparities in American Indian and Alaska Native Persons

Hepatocellular CarcinomaHepatitis BCirrhosis, Liver
University of Washington200 enrolled1 locationNCT05304234